CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM13200
Family Name Non-receptor tyrosine-protein kinase TYK2 ligand SureCN12989140 family
No. of Seeds 3 No. of Other Members 0
Family Centroid CFAMM00421047 Functional Category Bioactive
Superfamily Metabotropic glutamate receptor 5 Ligand 3-chloro-n-(6-chloropyridin-2-yl)benzamide Superfamily
Class Class 2337

Cousin Family NamesSeedsMembers
Reverse transcriptase Inhibitor Nevirapine Family 23 640
Transient receptor potential cation channel subfamily V member... 16 295
RAC-gamma serine/threonine-protein kinase Inhibitor AZD5363 Fa... 35 69
Histone deacetylase 6 Inhibitor ACY-1215 Family 10 230
Bacterial outer membrane Inhibitor HKI-9924129 Family 19 85
D(2) dopamine receptor and D(3) dopamine receptor Ligand Azape... 7 102
Cyclin-dependent kinase 1 Inhibitor CGP-60474 Family 14 103
Bifunctional epoxide hydrolase 2 Inhibitor 6-amino-n-(2,4-dich... 10 116
Cannabinoid receptor 1 and Cannabinoid receptor 2 Ligand 6-(4-... 3 6
5-hydroxytryptamine receptor 1F and 5-hydroxytryptamine recept... 8 12
Adenosine receptor A3 ligand AGN-PC-07N4XX family 6 10
Serine/threonine-protein kinase mTOR and Phosphatidylinositol ... 2 12
RAC-alpha serine/threonine-protein kinase inhibitor SureCN4728... 11 6
Serine/threonine-protein kinase pim-2 and Serine/threonine-pro... 6 9
Cell division cycle 7-related protein kinase and Cyclin-depend... 2 9
Mitogen-activated protein kinase 13 and Mitogen-activated prot... 5 2
cGMP-dependent 3',5'-cyclic phosphodiesterase and cAMP and cAM... 8 13
Tyrosine-protein kinase JAK2 inhibitor AGN-PC-09QM1E family 8 15
Protein-tyrosine kinase 6 and KH domain-containing, RNA-bindin... 21 6
G1/S-specific cyclin-E2 and G1/S-specific cyclin-E1 inhibitor ... 5 10
Dipeptidyl peptidase 9 and Dipeptidyl peptidase 8 inhibitor 3-... 3 6
Cell division cycle 7-related protein kinase and Dual specific... 3 1
C-C chemokine receptor type 4 ligand [4-[4-[(2,4-dichloropheny... 4 4
Tyrosine-protein kinase Lck and Vascular endothelial growth fa... 3 0
Tyrosine-protein kinase JAK2 inhibitor N-[3-(3-chlorophenyl)-1... 12 4
P2X purinoceptor 7 inhibitor SureCN109432 family 10 28
P2X purinoceptor 7 inhibitor SureCN109149 family 8 1
P2X purinoceptor 7 inhibitor SureCN9931311 family 2 0
P2X purinoceptor 7 inhibitor SureCN113576 family 2 1
Corticosteroid 11-beta-dehydrogenase isozyme 1 inhibitor (4-am... 2 1
Epithelial discoidin domain-containing receptor 1 and Mast/ste... 1 0
Metabotropic glutamate receptor 5 ligand 5-(4-chlorophenyl)-1,... 3 1
Non-receptor tyrosine-protein kinase TYK2 ligand AGN-PC-0D0YSZ... 10 0
Non-receptor tyrosine-protein kinase TYK2 ligand AGN-PC-0D0Z0U... 2 0
Non-receptor tyrosine-protein kinase TYK2 ligand SureCN3514789... 1 0
cAMP-specific 3',5'-cyclic phosphodiesterase 4B inhibitor AGN-... 1 1
B1 bradykinin receptor ligand SureCN6045889 family 4 9
Proto-oncogene tyrosine-protein kinase Src and Fibroblast grow... 3 4


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00421047 CHEMBL2387219 Bioactive SureCN12989140
CFAMM00421046 CHEMBL2387126 Bioactive SureCN3563270

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

27518 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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