CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM13209
Family Name Histamine H3 receptor and Histamine receptor H3 ligand 1-[4-[3-(2-methylpyrrolidin-1-yl)pyrrolidin-1-yl]phenyl]-3-(thiophen-2-ylmethyl)urea family
No. of Seeds 2 No. of Other Members 3
Family Centroid CFAMM00421076 Functional Category Bioactive
Superfamily Survival motor neuron protein and Histamine H3 receptor Binder Superfamily
Class Class 4499

Cousin Family NamesSeedsMembers
Nitric oxide synthase, brain and Nitric oxide synthase, induci... 2 35
Coagulation factor X and Trypsin-1 inhibitor AGN-PC-0884YN family 1 1
Nitric oxide synthase, brain and Nitric oxide synthase, endoth... 1 2
Acyl-CoA:cholesterol acyltransferase inhibitor SureCN8810690 f... 6 3
Mu-type opioid receptor ligand 1-phenyl-3-[[(3S)-2-[[(2R)-1-(t... 1 1
Acyl-CoA:cholesterol acyltransferase inhibitor 1-[2,6-di(propa... 3 0


External ID

Functional Category

Molecule Name

CFAMM00421077 CHEMBL2387289 Bioactive 1-[3-methyl-4-[3-(2-methylpyrrolidin-1-yl)pyrrolidin-1-yl]phenyl]-3-(thiophen-2-ylmethyl)urea
CFAMM00421076 CHEMBL2387288 Bioactive 1-[4-[3-(2-methylpyrrolidin-1-yl)pyrrolidin-1-yl]phenyl]-3-(thiophen-2-ylmethyl)urea

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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Computer-aided Drug Design
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