CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM13210
Family Name Histamine H3 receptor and Histamine receptor H3 ligand 1-(3,5-dichlorophenyl)-3-[2-methyl-4-[3-(2-methylpyrrolidin-1-yl)pyrrolidin-1-yl]phenyl]urea family
No. of Seeds 4 No. of Other Members 0
Family Centroid CFAMM00294225 Functional Category Bioactive
Superfamily Carbonic anhydrase 1 and Carbonic anhydrase 2 Binder Superfamily 22
Class Class 2078

Cousin Family NamesSeedsMembers
D(2) dopamine receptor ligand diphenylbutylpiperidine derivati... 10 157
Dopamine receptor Ligand Domperidone Family 2 21
D(2) dopamine receptor ligand diphenylbutylpiperidine derivati... 43 161
Bifunctional epoxide hydrolase 2 Inhibitor 1-(3-chloro-phenyl)... 5 50
Cannabinoid receptor 1 Ligand 1-(bis(4-chlorophenyl)methyl)-3-... 4 44
5-hydroxytryptamine receptor 3A Ligand 1-(biphenyl-4-yl)-3-(4-... 20 67
Induced myeloid leukemia cell differentiation protein Mcl-1 an... 2 7
5-hydroxytryptamine receptor 3B and 5-hydroxytryptamine recept... 4 24
D(3) dopamine receptor and D(2) dopamine receptor ligand 1-(3-... 6 12
Melanin-concentrating hormone receptor 1 ligand 3-(3-chloro-4-... 8 24
D(3) dopamine receptor and D(2) dopamine receptor ligand 3-[4-... 4 23
Melanin-concentrating hormone receptor 1 ligand 1-[[4-[4-(3-cy... 14 23
Melanin-concentrating hormone receptor 1 ligand SureCN3845324 ... 7 4
Melanin-concentrating hormone receptor 1 ligand SureCN14265737... 2 0
D(3) dopamine receptor and D(2) dopamine receptor ligand RGH-1... 8 0
Nociceptin receptor ligand 2-[3-[1-[(1R)-1,2-dihydroacenaphthy... 2 0
Histamine H3 receptor and Histamine receptor H3 ligand N-[4-[3... 5 1
Histamine H3 receptor and Histamine receptor H3 ligand 1-cyclo... 3 4
Melanin-concentrating hormone receptor 1 ligand SureCN13451707... 3 1
D(3) dopamine receptor and D(2) dopamine receptor ligand 1-(3-... 4 3
Potassium voltage-gated channel subfamily H member 2 and D(3) ... 3 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00421079 CHEMBL2387290 Bioactive 1-[(3,5-dichlorophenyl)methyl]-3-[4-[3-(2-methylpyrrolidin-1-yl)pyrrolidin-1-yl]phenyl]urea

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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