CFam Chemical Families Database
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Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM13219
Family Name Renin inhibitor (2S,4S,5S)-5-amino-6-[4-(2-chlorophenyl)-2,2-dimethyl-5-oxopiperazin-1-yl]-4-hydroxy-2-propan-2-yl-N-pyridin-2-ylhexanamide;(E)-but-2-enedioic acid family
No. of Seeds 7 No. of Other Members 1
Family Centroid CFAMM00421116 Functional Category Bioactive
Superfamily Renin and Coagulation factor X Binder Superfamily
Class Class 3069

Cousin Family NamesSeedsMembers
Transient receptor potential cation channel subfamily V member... 16 295
Cannabinoid receptor 1 and Cannabinoid receptor 2 Ligand 6-(4-... 3 6
C-C chemokine receptor type 4 ligand [4-[4-[(2,4-dichloropheny... 4 4
Renin inhibitor (E)-but-2-enedioic acid;(3S,5R)-5-[4-(2-chloro... 6 8
P2X purinoceptor 7 inhibitor SureCN1635928 family 4 4
Renin inhibitor (2S,4S,5S)-5-amino-6-[4-(2-chlorophenyl)-2,2-d... 3 0
Integrin alpha-V and Integrin beta-6 inhibitor SureCN12259087 ... 3 4


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00421113 CHEMBL2387561 Bioactive (2S,4S,5S)-5-amino-6-[4-(2-chlorophenyl)-2,2-dimethyl-5-oxopiperazin-1-yl]-4-hydroxy-N-(6-methylpyridin-2-yl)-2-propan-2-ylhexanamide;(E)-but-2-enedioic acid
CFAMM00421112 CHEMBL2387562 Bioactive (2R,4S,5S)-5-amino-6-[4-(2-chlorophenyl)-2,2-dimethyl-5-oxopiperazin-1-yl]-2-ethyl-4-hydroxy-N-(3-methylpyridin-2-yl)hexanamide;(E)-but-2-enedioic acid
CFAMM00421111 CHEMBL2387559 Bioactive (2S,4S,5S)-5-amino-6-[4-(2-chlorophenyl)-2,2-dimethyl-5-oxopiperazin-1-yl]-N-(3,5-difluoropyridin-2-yl)-4-hydroxy-2-propan-2-ylhexanamide;(E)-but-2-enedioic acid
CFAMM00421110 CHEMBL2387558 Bioactive (2R,4S,5S)-5-amino-6-[4-(2-chlorophenyl)-2,2-dimethyl-5-oxopiperazin-1-yl]-2-ethyl-N-(5-fluoropyridin-2-yl)-4-hydroxyhexanamide;(E)-but-2-enedioic acid
CFAMM00421116 CHEMBL2387547 Bioactive (2S,4S,5S)-5-amino-6-[4-(2-chlorophenyl)-2,2-dimethyl-5-oxopiperazin-1-yl]-4-hydroxy-2-propan-2-yl-N-pyridin-2-ylhexanamide;(E)-but-2-enedioic acid
CFAMM00421115 CHEMBL2387557 Bioactive (2S,4S,5S)-5-amino-6-[4-(2-chlorophenyl)-2,2-dimethyl-5-oxopiperazin-1-yl]-N-(5-fluoropyridin-2-yl)-4-hydroxy-2-propan-2-ylhexanamide;(E)-but-2-enedioic acid
CFAMM00421114 CHEMBL2387560 Bioactive (2R,4S,5S)-5-amino-6-[4-(2-chlorophenyl)-2,2-dimethyl-5-oxopiperazin-1-yl]-2-ethyl-4-hydroxy-N-(4-methoxypyridin-2-yl)hexanamide;(E)-but-2-enedioic acid

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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