CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM13222
Family Name Renin inhibitor (2S,4S,5S)-5-amino-6-[4-(5-fluoro-2-methylphenyl)-2,2-dimethyl-5-oxopiperazin-1-yl]-4-hydroxy-N-(5-hydroxy-2-adamantyl)-2-propan-2-ylhexanamide;(E)-but-2-enedioic acid family
No. of Seeds 2 No. of Other Members 0
Family Centroid CFAMM00421117 Functional Category Bioactive
Superfamily Renin Binder Superfamily 8
Class Class 348

Cousin Family NamesSeedsMembers
Renin inhibitor SureCN9038274 family 3 8
Renin inhibitor (2S,4S,5S)-5-amino-N-(3-amino-2,2-dimethyl-3-o... 9 10
Renin inhibitor (2S,4S,5S)-5-amino-N-butyl-6-[4-(2-chloropheny... 30 3


External ID

Functional Category

Molecule Name

CFAMM00421118 CHEMBL2387575 Bioactive (2R,4S,5S)-5-amino-2-ethyl-6-[4-(5-fluoro-2-methylphenyl)-2,2-dimethyl-5-oxopiperazin-1-yl]-4-hydroxy-N-(5-hydroxy-2-adamantyl)hexanamide;(E)-but-2-enedioic acid
CFAMM00421117 CHEMBL2387574 Bioactive (2S,4S,5S)-5-amino-6-[4-(5-fluoro-2-methylphenyl)-2,2-dimethyl-5-oxopiperazin-1-yl]-4-hydroxy-N-(5-hydroxy-2-adamantyl)-2-propan-2-ylhexanamide;(E)-but-2-enedioic acid

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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