CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM13232
Family Name Renin and Cytochrome P450 3A4 inhibitor AGN-PC-046RG9 family
No. of Seeds 8 No. of Other Members 28
Family Centroid CFAMM00421181 Functional Category Bioactive
Superfamily Melanin-concentrating hormone receptor 1 Binder Superfamily
Class Class 2246

Cousin Family NamesSeedsMembers
D(3) dopamine receptor Ligand PF-217830 Family 21 7
Melanin-concentrating hormone receptor 1 Ligand Gnf-pf-2322 Fa... 3 95
Melanin-concentrating hormone receptor 1 Ligand ADS-102891 Family 6 51
5-hydroxytryptamine receptor 1A and 5-hydroxytryptamine recept... 17 49
Epidermal growth factor receptor ligand N-[4-(3-chloro-4-fluor... 6 47
Adenosine kinase inhibitor 5-[3-(4-methoxyphenyl)propyl]-6-[2-... 2 11
Prelamin-A/C and Nuclear receptor ROR-gamma ligand CHEMBL13704... 1 7
Thyroid hormone receptor beta and Ferritin light chain ligand ... 1 35
Dihydrofolate reductase inhibitor AC1LA5HU family 8 4
Prostaglandin D2 receptor ligand 2-[3-[2-methoxy-6-[2-(4-metho... 4 12
Prostaglandin D2 receptor ligand 1-[3-[2-methoxy-6-[2-(4-metho... 6 16
Integrin beta-1 and Integrin alpha-4 inhibitor SureCN2059024 f... 6 3
Cholecystokinin receptor type A ligand AGN-PC-0A9ULH family 8 8
Cyclin-dependent kinase 4 and G1/S-specific cyclin-D1 inhibito... 9 10
Epidermal growth factor receptor ligand SureCN4454332 family 18 5
Nitric oxide synthase, inducible inhibitor 2-[1-(2-imidazol-1-... 4 3
Angiopoietin-1 receptor and Vascular endothelial growth factor... 4 6
Epidermal growth factor receptor ligand SureCN2989664 family 5 2
Bifunctional dihydrofolate reductase-thymidylate synthase inhi... 2 6
5-hydroxytryptamine receptor 1A and 5-hydroxytryptamine recept... 18 0
5-hydroxytryptamine receptor 1D and 5-hydroxytryptamine recept... 2 0
cGMP-specific 3',5'-cyclic phosphodiesterase inhibitor AGN-PC-... 3 1
Acyl-CoA desaturase inhibitor SureCN1182546 family 2 5
Dihydrofolate reductase inhibitor 5-[3-(3-methoxy-5-morpholin-... 2 0
D(3) dopamine receptor and D(2) dopamine receptor ligand AGN-P... 2 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00421182 CHEMBL391463 Bioactive 1,4-benzoxazin-3-one, 33
CFAMM00421188 CHEMBL239496 Bioactive AGN-PC-00IQPG
CFAMM00421181 CHEMBL239078 Bioactive AGN-PC-046RG9
CFAMM00421199 CHEMBL241032 Bioactive AGN-PC-046RGI
CFAMM00421165 CHEMBL240598 Bioactive AGN-PC-046RGF
CFAMM00421178 CHEMBL398584 Bioactive AGN-PC-046RG3
CFAMM00421196 CHEMBL393364 Bioactive AGN-PC-046RG8
CFAMM00421176 CHEMBL240391 Bioactive AGN-PC-046RGE

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

22954 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


All rights reserved.

   
 
 
Computer-aided Drug Design
about BIDD |  databases |  software |  teaching |  research |  links

 

Department of Computational Science | National University of Singapore | Blk S17, 3 Science Drive 2, Singapore 117543