CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM13236
Family Name Prostaglandin G/H synthase 2 inhibitor 1-(3,4-difluorophenyl)-2-methyl-5-(4-methylsulfonylphenyl)pyrrole-3-carbonitrile family
No. of Seeds 1 No. of Other Members 3
Family Centroid CFAMM00421245 Functional Category Bioactive
Superfamily Prostaglandin G/H synthase 2 and Prostaglandin D2 receptor 2 Binder Superfamily
Class Class 3264

Cousin Family NamesSeedsMembers
Prostaglandin G/H synthase 2 Inhibitor Etoricoxib Family 2 99
5-hydroxytryptamine receptor 6 Ligand 4-(1h-indol-1-ylsulfonyl... 7 79
5-hydroxytryptamine receptor 2A and 5-hydroxytryptamine recept... 14 19
5-hydroxytryptamine receptor 6 Ligand 6-tosyl-1,2,3,4,5,6-hexa... 4 22
Prostaglandin G/H synthase 2 Inhibitor 2-(4-(methylsulfonyl)ph... 7 33
Prostaglandin G/H synthase 2 Inhibitor 1-(4-(methylsulfonyl)ph... 1 2
5-hydroxytryptamine receptor 6 ligand CHEMBL1950756 family 8 8
Prostaglandin G/H synthase 2 inhibitor AGN-PC-03VWKZ family 2 34
Substance-K receptor and Cytochrome P450 2D6 ligand 158848-32-... 4 4
Carbonic anhydrase 9 and Carbonic anhydrase 2 inhibitor 4-[2-(... 2 6
5-hydroxytryptamine receptor 2A ligand SureCN5215979 family 2 10
Prostaglandin D2 receptor 2 ligand 2-[5-fluoro-2-methyl-3-[(4-... 3 5
Prostaglandin G/H synthase 2 and Prostaglandin G/H synthase 1 ... 4 68
5-hydroxytryptamine receptor 6 ligand 9-(benzenesulfonyl)-N,N-... 7 1
5-hydroxytryptamine receptor 6 ligand 9-(benzenesulfonyl)-N,N-... 2 0
Prostaglandin G/H synthase 2 inhibitor 1-(3-fluorophenyl)-2-me... 1 5
Prostaglandin G/H synthase 2 inhibitor AGN-PC-03VWQ9 family 3 5
Prostaglandin G/H synthase 2 inhibitor AGN-PC-03NCPN family 4 0
Prostaglandin G/H synthase 2 inhibitor SureCN6345015 family 6 1
Prostaglandin G/H synthase 2 inhibitor AGN-PC-03NCPD family 6 2


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00421245 CHEMBL2391055 Bioactive 1-(3,4-difluorophenyl)-2-methyl-5-(4-methylsulfonylphenyl)pyrrole-3-carbonitrile

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

48716 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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