CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM1324
Family Name Pol polyprotein inhibitor (2S)-1-[(2S,4R)-4-benzyl-2-hydroxy-5-[[(2R)-2-hydroxy-2,3-dihydro-1H-inden-1-yl]amino]-5-oxopentyl]-N-tert-butyl-4-(furo[3,2-c]pyridin-2-ylmethyl)piperazine-2-carboxamide family
No. of Seeds 12 No. of Other Members 0
Family Centroid CFAMM00322182 Functional Category Bioactive
Superfamily Beta-3 adrenergic receptor and Pol polyprotein Binder Superfamily
Class Class 630

Cousin Family NamesSeedsMembers
Pol polyprotein inhibitor AC1LARNY family 28 17
Pol polyprotein and Cytochrome P450 3A4 inhibitor P3 arylpyrro... 19 1
Pol polyprotein inhibitor ethyl)-amide family 4 0
Pol polyprotein inhibitor pyridylfuran analog 14 family 6 0
Beta-3 adrenergic receptor ligand 6-[4-[2-[[(2S)-3-[(3,3-dimet... 6 7
Substance-P receptor ligand (4R)-N-[(2R)-1-[benzyl(methyl)amin... 1 4
Tyrosine-protein kinase JAK3 and Activated CDC42 kinase 1 inhi... 4 1


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00322172 CHEMBL432633 Bioactive AGN-PC-074Z5F
CFAMM00322178 CHEMBL325354 Bioactive (2S)-1-[(2S,4R)-4-benzyl-2-hydroxy-5-[[(2R)-2-hydroxy-2,3-dihydro-1H-inden-1-yl]amino]-5-oxopentyl]-N-tert-butyl-4-(furo[2,3-c]pyridin-2-ylmethyl)piperazine-2-carboxamide
CFAMM00322177 CHEMBL81840 Bioactive AC1LA3TJ
CFAMM00322176 CHEMBL116052 Bioactive 1-[4-benzyl-2-hydroxy-5-[(2-hydroxy-2,3-dihydro-1H-inden-1-yl)amino]-5-oxopentyl]-N-tert-butyl-4-[[5-(hydroxymethyl)furo[2,3-b]pyridin-2-yl]methyl]piperazine-2-carboxamide
CFAMM00322175 CHEMBL325181 Bioactive (2S)-1-[(2S,4R)-4-benzyl-2-hydroxy-5-[[(2R)-2-hydroxy-2,3-dihydro-1H-inden-1-yl]amino]-5-oxopentyl]-N-tert-butyl-4-[(4-chlorofuro[2,3-b]pyridin-5-yl)methyl]piperazine-2-carboxamide
CFAMM00322183 CHEMBL2062137 Bioactive (2S)-1-[(2S,4R)-4-benzyl-2-hydroxy-5-[[(1S,2R)-2-hydroxy-2,3-dihydro-1H-inden-1-yl]amino]-5-oxopentyl]-N-tert-butyl-4-(furo[2,3-b]pyridin-5-ylmethyl)piperazine-2-carboxamide
CFAMM00322174 CHEMBL78876 Bioactive AC1LAX1D
CFAMM00322182 CHEMBL324025 Bioactive (2S)-1-[(2S,4R)-4-benzyl-2-hydroxy-5-[[(2R)-2-hydroxy-2,3-dihydro-1H-inden-1-yl]amino]-5-oxopentyl]-N-tert-butyl-4-(furo[3,2-c]pyridin-2-ylmethyl)piperazine-2-carboxamide
CFAMM00322180 CHEMBL116845 Bioactive (2S)-1-[(2S,4R)-4-benzyl-2-hydroxy-5-[[(2R)-2-hydroxy-2,3-dihydro-1H-inden-1-yl]amino]-5-oxopentyl]-N-tert-butyl-4-(furo[2,3-b]pyridine-5-carbonyl)piperazine-2-carboxamide
CFAMM00322173 CHEMBL408413 Bioactive (2S)-1-[(2S,4R)-4-benzyl-2-hydroxy-5-[[(2R)-2-hydroxy-2,3-dihydro-1H-inden-1-yl]amino]-5-oxopentyl]-N-tert-butyl-4-(furo[3,2-b]pyridin-6-ylmethyl)piperazine-2-carboxamide
CFAMM00322181 CHEMBL324516 Bioactive AGN-PC-074Z5G
CFAMM00322179 CHEMBL325013 Bioactive (2S)-1-[(2S,4R)-4-benzyl-2-hydroxy-5-[[(2R)-2-hydroxy-2,3-dihydro-1H-inden-1-yl]amino]-5-oxopentyl]-N-tert-butyl-4-[(6-methylfuro[3,2-c]pyridin-2-yl)methyl]piperazine-2-carboxamide

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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