CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM13243
Family Name Integrin beta-1 and Integrin alpha-4 inhibitor (2S)-2-[[1-[2-(carbamoylamino)ethyl]cyclopentanecarbonyl]amino]-3-[4-[(2,6-dichlorobenzoyl)amino]phenyl]propanoic acid family
No. of Seeds 12 No. of Other Members 2
Family Centroid CFAMM00421293 Functional Category Bioactive
Superfamily Integrin beta-1 and Integrin alpha-4 Binder Superfamily 6
Class Class 2592

Cousin Family NamesSeedsMembers
Glycine receptor subunit beta Ligand Gw 468816 Family 4 67
Integrin beta-1 Inhibitor R411 Family 33 44
Cholecystokinin receptor type A Ligand VL-1499 Family 12 133
Integrin beta-2 and Intercellular adhesion molecule 1 inhibito... 3 18
Integrin beta-1 and Integrin alpha-4 inhibitor (E)-3-[4-[(2,6-... 3 1
Integrin beta-1 and Integrin alpha-4 inhibitor (2S)-3-[4-[(2,6... 7 3
Integrin beta-1 and Integrin alpha-4 inhibitor SureCN6823871 f... 9 0
Integrin alpha-4 and Integrin beta-7 inhibitor (2S)-2-[(2,6-di... 9 27
Integrin beta-1 and Integrin alpha-4 inhibitor (2S)-2-[(2,6-di... 2 4
Integrin beta-1 and Integrin alpha-4 inhibitor (2S)-2-[(4-brom... 2 0
Integrin beta-1 and Integrin alpha-4 inhibitor SureCN5367895 f... 3 0
Integrin beta-1 and Integrin alpha-4 inhibitor (2S)-2-[(3-brom... 1 0
Glucagon receptor and Adenylate cyclase type 1 ligand AGN-PC-0... 1 0
[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme ... 1 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00421296 CHEMBL82987 Bioactive (2S)-2-[[1-(cyanomethyl)cyclopentanecarbonyl]amino]-3-[4-[(2,6-dichlorobenzoyl)amino]phenyl]propanoic acid
CFAMM00421289 CHEMBL315464 Bioactive (2S)-3-[4-[(2,6-dichlorobenzoyl)amino]phenyl]-2-[[1-[2-(methylcarbamothioylamino)ethyl]cyclopentanecarbonyl]amino]propanoic acid
CFAMM00421295 CHEMBL84088 Bioactive (2S)-3-[4-[(2,6-dichlorobenzoyl)amino]phenyl]-2-[[1-(4-oxopentyl)cyclopentanecarbonyl]amino]propanoic acid
CFAMM00421294 CHEMBL84428 Bioactive (2S)-3-[4-[(2,6-dichlorobenzoyl)amino]phenyl]-2-[[1-[2-(phenylcarbamoylamino)ethyl]cyclopentanecarbonyl]amino]propanoic acid
CFAMM00421287 CHEMBL310351 Bioactive (2S)-2-[[1-[(4-cyanophenyl)methyl]cyclopentanecarbonyl]amino]-3-[4-[(2,6-dichlorobenzoyl)amino]phenyl]propanoic acid
CFAMM00421293 CHEMBL309506 Bioactive (2S)-2-[[1-[2-(carbamoylamino)ethyl]cyclopentanecarbonyl]amino]-3-[4-[(2,6-dichlorobenzoyl)amino]phenyl]propanoic acid
CFAMM00421286 CHEMBL81814 Bioactive (2S)-2-[[1-(2-azidoethyl)cyclopentanecarbonyl]amino]-3-[4-[(2,6-dichlorobenzoyl)amino]phenyl]propanoic acid
CFAMM00421299 CHEMBL311706 Bioactive (2S)-3-[4-[(2,6-dichlorobenzoyl)amino]phenyl]-2-[[1-[2-[(2,2,2-trifluoroacetyl)amino]ethyl]cyclopentanecarbonyl]amino]propanoic acid
CFAMM00421292 CHEMBL311546 Bioactive (2S)-2-[[1-(4-cyanobutyl)cyclopentanecarbonyl]amino]-3-[4-[(2,6-dichlorobenzoyl)amino]phenyl]propanoic acid
CFAMM00421298 CHEMBL79984 Bioactive SureCN6632476
CFAMM00421291 CHEMBL2391315 Bioactive (2S)-2-[(3-tert-butyl-5-methyl-4H-1,2-oxazole-5-carbonyl)amino]-3-[4-[(2,6-dichlorobenzoyl)amino]phenyl]propanoic acid
CFAMM00421297 CHEMBL79694 Bioactive SureCN6627353

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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