CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM13245
Family Name Nicotinamide phosphoribosyltransferase inhibitor 1-[4-(8-oxa-3-azabicyclo[3.2.1]octan-3-ylsulfonyl)phenyl]-3-(pyridin-3-ylmethyl)urea family
No. of Seeds 5 No. of Other Members 4
Family Centroid CFAMM00421308 Functional Category Bioactive
Superfamily Prelamin-A/C and Nicotinamide phosphoribosyltransferase Binder Superfamily
Class Class 1174

Cousin Family NamesSeedsMembers
Solute carrier family 12 member 1 Inhibitor Torasemide Family 13 75
Corticosteroid 11-beta-dehydrogenase isozyme 1 Inhibitor 2-(4-... 8 25
Carbonic anhydrase 1 and Carbonic anhydrase 2 Inhibitor 4-(2-p... 2 9
Beta-3 adrenergic receptor and Beta-2 adrenergic receptor liga... 19 53
Thyrotropin receptor and Huntingtin ligand CHEMBL1333081 family 1 2
Nicotinamide phosphoribosyltransferase and Prelamin-A/C inhibi... 1 0
Pol polyprotein inhibitor Lysine Sulfonamide 6h family 1 1
Neuronal acetylcholine receptor subunit alpha-7 ligand 1-(4-me... 1 0
Pol polyprotein inhibitor AC1LAHQ9 family 8 15
cAMP-specific 3',5'-cyclic phosphodiesterase 4A and cAMP-speci... 4 0
Nicotinamide phosphoribosyltransferase and Cytochrome P450 2C9... 4 5
Nicotinamide phosphoribosyltransferase inhibitor 1-[4-(1-methy... 1 4
Nicotinamide phosphoribosyltransferase inhibitor N-[[4-(3,5-di... 4 8
Nicotinamide phosphoribosyltransferase and Cytochrome P450 2C9... 1 0
Beta-3 adrenergic receptor ligand N-[4-[2-[[(2R)-2-hydroxy-2-p... 4 10


External ID

Functional Category

Molecule Name

CFAMM00421309 CHEMBL2393173 Bioactive 1-[4-[[(1S,3S)-3-hydroxycyclohexyl]sulfamoyl]phenyl]-3-(pyridin-3-ylmethyl)urea
CFAMM00421315 CHEMBL2393158 Bioactive 1-[4-(3-oxa-8-azabicyclo[3.2.1]octan-8-ylsulfonyl)phenyl]-3-(pyridin-3-ylmethyl)urea
CFAMM00421308 CHEMBL2391568 Bioactive 1-[4-(8-oxa-3-azabicyclo[3.2.1]octan-3-ylsulfonyl)phenyl]-3-(pyridin-3-ylmethyl)urea
CFAMM00421310 CHEMBL2393172 Bioactive 1-[4-[(4-hydroxycyclohexyl)sulfamoyl]phenyl]-3-(pyridin-3-ylmethyl)urea

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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