CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM13246
Family Name Nicotinamide phosphoribosyltransferase and Cytochrome P450 2C9 inhibitor 1-[4-(benzenesulfonyl)phenyl]-3-(pyridin-3-ylmethyl)urea family
No. of Seeds 4 No. of Other Members 5
Family Centroid CFAMM00073922 Functional Category Bioactive
Superfamily Nicotinamide phosphoribosyltransferase and Cytochrome P450 2C9 Binder Superfamily
Class Class 428

Cousin Family NamesSeedsMembers
Solute carrier family 12 member 1 Inhibitor Torasemide Family 13 75
Dihydropterin pyrophosphokinase-dihydropteroate synthase inhib... 5 60
Corticosteroid 11-beta-dehydrogenase isozyme 1 Inhibitor 2-(4-... 8 25
Potassium voltage-gated channel subfamily H member 2 Ligand AZ... 21 42
Hepatocyte growth factor receptor Ligand 3-(phenylsulfonyl)-1h... 17 59
Carbonic anhydrase 1 and Carbonic anhydrase 2 Inhibitor 4-(2-p... 2 9
Tyrosine-protein kinase JAK2 inhibitor AGN-PC-07ZB89 family 6 13
Protein farnesyltransferase/geranylgeranyltransferase type-1 s... 4 4
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subun... 4 27
Thyrotropin receptor and Huntingtin ligand CHEMBL1333081 family 1 2
Nicotinamide phosphoribosyltransferase and Prelamin-A/C inhibi... 1 0
Insulin-like growth factor 1 receptor ligand AGN-PC-09LNNY family 1 10
Vascular endothelial growth factor receptor 2 ligand urea deri... 3 9
Vascular endothelial growth factor receptor 2 ligand urea deri... 2 0
Neuronal acetylcholine receptor subunit alpha-7 ligand 1-(4-me... 1 0
cAMP-specific 3',5'-cyclic phosphodiesterase 4A and cAMP-speci... 4 0
Nicotinamide phosphoribosyltransferase inhibitor 1-[4-(8-oxa-3... 5 4
Nicotinamide phosphoribosyltransferase inhibitor 1-[4-(1-methy... 1 4
Mitogen-activated protein kinase 8 and Mitogen-activated prote... 4 5
Nicotinamide phosphoribosyltransferase inhibitor N-[[4-(3,5-di... 4 8
Nicotinamide phosphoribosyltransferase inhibitor 2-[[4-(3-chlo... 1 0
Nicotinamide phosphoribosyltransferase and Cytochrome P450 2C9... 1 0
Nicotinamide phosphoribosyltransferase inhibitor N-[[4-(benzen... 4 0
Cannabinoid receptor 2 ligand 1-(benzenesulfonyl)-N-quinolin-3... 2 2
Focal adhesion kinase 1 and Protein-tyrosine kinase 2-beta inh... 1 1
Transient receptor potential cation channel subfamily V member... 3 2
Protein-glutamine gamma-glutamyltransferase 2 and Coagulation ... 1 0
Protein-glutamine gamma-glutamyltransferase 2 and Coagulation ... 1 2
Protein-tyrosine kinase 2-beta inhibitor 4-N-[(1R,2R)-2-(dimet... 1 0
Transient receptor potential cation channel subfamily V member... 2 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00421319 CHEMBL2391574 Bioactive 1-[4-(4-chlorophenyl)sulfonylphenyl]-3-(pyridin-3-ylmethyl)urea
CFAMM00421323 CHEMBL2393183 Bioactive 1-[(6-aminopyridin-3-yl)methyl]-3-[4-(benzenesulfonyl)phenyl]urea

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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