CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM13250
Family Name C-C chemokine receptor type 1 and Chemokine (C-C motif) receptor 1 ligand [2-[(2S)-3-(5-chlorospiro[3H-1-benzofuran-2,4'-piperidine]-1'-yl)-2-hydroxypropoxy]-4-hydroxyphenyl]-[(3R)-3-hydroxypyrrolidin-1-yl]methanone family
No. of Seeds 11 No. of Other Members 15
Family Centroid CFAMM00421368 Functional Category Bioactive with Natural Product
Superfamily Cyclin-dependent kinase 1 and Cyclin-dependent kinase 2 Binder Superfamily
Class Class 288

Cousin Family NamesSeedsMembers
Cyclin-dependent kinase 2 Inhibitor Flavopiridol Family 4 124
C-C chemokine receptor type 5 Ligand GW873140 Family 6 78
Plasmepsin-2 Inhibitor PS-662477 Family 7 55
Leukotriene B4 receptor 1 Ligand SC-51146 Family 6 315
Urotensin-2 receptor Ligand SB-436811 Family 6 71
Multidrug resistance protein 1 inhibitor 1-[2-[(2R)-3-[4-(2,3-... 2 41
C-C chemokine receptor type 3 and Histamine H1 receptor ligand... 3 1
C-C chemokine receptor type 1 and Chemokine (C-C motif) recept... 1 16
C-C chemokine receptor type 1 ligand [2-[(2S)-3-(5-chlorospiro... 3 0
C-C chemokine receptor type 1 ligand 2-[(2S)-3-(5-chlorospiro[... 2 3
Histamine H3 receptor and Sodium-dependent serotonin transport... 14 3


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00421361 CHEMBL2391938 Bioactive 2-[(2S)-3-(5-chlorospiro[3H-1-benzofuran-2,4'-piperidine]-1'-yl)-2-hydroxypropoxy]-N-cyclopropyl-4-methoxybenzamide
CFAMM00421374 CHEMBL2391803 Bioactive [5-chloro-2-[(2S)-3-(5-chlorospiro[3H-1-benzofuran-2,4'-piperidine]-1'-yl)-2-hydroxypropoxy]-4-hydroxyphenyl]-[(3S)-3-hydroxypyrrolidin-1-yl]methanone
CFAMM00421367 CHEMBL2391797 Bioactive [2-[(2S)-3-(5-chlorospiro[3H-1-benzofuran-2,4'-piperidine]-1'-yl)-2-hydroxypropoxy]-4-hydroxyphenyl]-[(3R)-3-(dimethylamino)pyrrolidin-1-yl]methanone
CFAMM00421380 CHEMBL2391804 Bioactive [2-[(2S)-3-(5-chlorospiro[3H-1-benzofuran-2,4'-piperidine]-1'-yl)-2-hydroxypropoxy]-4-hydroxyphenyl]-[(3S)-3-hydroxypyrrolidin-1-yl]methanone
CFAMM00421373 CHEMBL2391808 Bioactive [2-[(2S)-3-(5-chlorospiro[3H-1-benzofuran-2,4'-piperidine]-1'-yl)-2-hydroxypropoxy]-4-hydroxyphenyl]-pyrrolidin-1-ylmethanone
CFAMM00421372 CHEMBL2391809 Bioactive [2-[(2S)-3-(5-chlorospiro[3H-1-benzofuran-2,4'-piperidine]-1'-yl)-2-hydroxypropoxy]-4-hydroxyphenyl]-piperidin-1-ylmethanone
CFAMM00421378 CHEMBL2391806 Bioactive [2-[(2S)-3-(5-chlorospiro[3H-1-benzofuran-2,4'-piperidine]-1'-yl)-2-hydroxypropoxy]-4-hydroxyphenyl]-[(3S)-3-methoxypyrrolidin-1-yl]methanone
CFAMM00421364 CHEMBL2391810 Bioactive [2-[(2S)-3-(5-chlorospiro[3H-1-benzofuran-2,4'-piperidine]-1'-yl)-2-hydroxypropoxy]-4-hydroxyphenyl]-(4-hydroxypiperidin-1-yl)methanone
CFAMM00421370 CHEMBL2391793 Bioactive 2-[(2S)-3-(5-chlorospiro[3H-1-benzofuran-2,4'-piperidine]-1'-yl)-2-hydroxypropoxy]-4-hydroxy-N-methylbenzamide
CFAMM00421369 CHEMBL2391795 Bioactive 2-[(2S)-3-(5-chlorospiro[3H-1-benzofuran-2,4'-piperidine]-1'-yl)-2-hydroxypropoxy]-N-cyclopropyl-4-hydroxybenzamide
CFAMM00421368 CHEMBL2391796 Bioactive [2-[(2S)-3-(5-chlorospiro[3H-1-benzofuran-2,4'-piperidine]-1'-yl)-2-hydroxypropoxy]-4-hydroxyphenyl]-[(3R)-3-hydroxypyrrolidin-1-yl]methanone

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

46363 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


All rights reserved.

   
 
 
Computer-aided Drug Design
about BIDD |  databases |  software |  teaching |  research |  links

 

Department of Computational Science | National University of Singapore | Blk S17, 3 Science Drive 2, Singapore 117543