CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM13251
Family Name C-C chemokine receptor type 1 and Chemokine (C-C motif) receptor 1 ligand 2-[(2S)-3-(5-fluorospiro[3H-1-benzofuran-2,4'-piperidine]-1'-yl)-2-hydroxypropoxy]-4-hydroxy-N-methylbenzamide family
No. of Seeds 1 No. of Other Members 16
Family Centroid CFAMM00238415 Functional Category Bioactive
Superfamily Cyclin-dependent kinase 1 and Cyclin-dependent kinase 2 Binder Superfamily
Class Class 288

Cousin Family NamesSeedsMembers
Alpha-1 adrenergic receptor ligand arylethanolamine derivative... 4 37
Muscarinic acetylcholine receptor Ligand Flavoxate Family 9 350
Ipriflavone family 62 2480
Cyclin-dependent kinase 2 Inhibitor Flavopiridol Family 4 124
C-C chemokine receptor type 5 Ligand GW873140 Family 6 78
Integrin alpha-4 Inhibitor Firategrast Family 3 93
Cytochrome P450 2D6 and Delta-type opioid receptor Ligand 4-(s... 17 381
Plasmepsin-2 Inhibitor PS-662477 Family 7 55
Leukotriene B4 receptor 1 Ligand SC-51146 Family 6 315
DNA-dependent protein kinase catalytic subunit Inhibitor 7-pro... 5 49
Histamine H3 receptor Ligand A-349821 Family 49 228
Acetylcholinesterase and Cholinesterase Inhibitor 3-[7-(benzyl... 22 303
Melanin-concentrating hormone receptor 1 Ligand N-(1-benzylpip... 9 57
Beta-2 adrenergic receptor Ligand Gnf-pf-1694 Family 4 70
Glycine receptor subunit beta Ligand ORG-25543 Family 10 153
Beta-2 adrenergic receptor and Beta-1 adrenergic receptor liga... 2 18
Multidrug resistance protein 1 inhibitor 1-[2-[(2R)-3-[4-(2,3-... 2 41
Peroxisome proliferator-activated receptor gamma ligand (9aS)-... 4 44
Melanin-concentrating hormone receptor 1 and Potassium voltage... 12 53
C-C chemokine receptor type 1 and Chemokine (C-C motif) recept... 11 15
C-C chemokine receptor type 1 ligand [2-[(2S)-3-(5-chlorospiro... 3 0
C-C chemokine receptor type 1 ligand 2-[(2S)-3-(5-chlorospiro[... 2 3
Histamine H3 receptor and Sodium-dependent serotonin transport... 2 11
Beta-3 adrenergic receptor and Beta-1 adrenergic receptor liga... 16 2
Breast cancer type 1 susceptibility protein and Huntingtin inh... 1 7
Cyclin-dependent kinase 5 and Cyclin-dependent kinase 5 activa... 2 110
Cyclin-dependent kinase 4 and G1/S-specific cyclin-D1 inhibito... 1 11
Putative NP ZINC08790868 Family 10 0
NP 2-((5-hydroxy-2,2-dimethyl-4-oxochroman-7-yl)oxy)-n-(3-meth... 18 0
NP 2-((1'-acetyl-4-oxospiro[chroman-2,4'-piperidin]-7-yl)oxy)-... 5 0


CFAM Mol ID

External ID

Functional Category

Molecule Name


Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

26413 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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