CFam Chemical Families Database
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Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM13256
Family Name Substance-P receptor ligand (2R,3R)-2-benzhydryl-N-(2-iodophenyl)-1-azabicyclo[2.2.2]octan-3-amine family
No. of Seeds 2 No. of Other Members 0
Family Centroid CFAMM00421409 Functional Category Bioactive
Superfamily 5-hydroxytryptamine receptor 1A and 5-hydroxytryptamine receptor 1B Ligand 1-naphthalen-2-yl-piperazine Superfamily
Class Class 2121

Cousin Family NamesSeedsMembers
Mu-type opioid receptor Ligand Fentanyl Family 9 647
Voltage-dependent T-type calcium channel subunit alpha-1H liga... 10 397
Noradrenergic re-uptake inhibitor Dibenzazepine Imipramine Family 8 178
D(2) dopamine receptor ligand diphenylbutylpiperidine derivati... 10 157
Histamine H1 receptor ligand piperazine derivative Cyclizine F... 16 140
Histamine H1 receptor Ligand Antazoline Family 5 57
D(2) dopamine receptor Ligand Nomifensine Family 6 100
Motilin receptor Ligand GSK962040 Family 30 457
Substance-P receptor Ligand Vestipitant Family 14 137
Serine/threonine-protein kinase mTOR Inhibitor CC-223 Family 12 135
Progesterone receptor Ligand 2,2,4-trimethyl-6-phenyl-1,2-dihy... 5 82
5-hydroxytryptamine receptor 1A and 5-hydroxytryptamine recept... 9 67
Delta-type opioid receptor and Kappa-type opioid receptor Liga... 8 32
Dipeptidyl peptidase 4 Inhibitor (3s,4r)-3-butyl-1-phenylpiper... 2 40
5-hydroxytryptamine receptor 7 Ligand UCM-5600 Family 15 46
Sodium-dependent dopamine transporter and Sodium-dependent nor... 28 71
5-hydroxytryptamine receptor 3A Ligand 1-(biphenyl-4-yl)-3-(4-... 20 67
5-hydroxytryptamine receptor 1A and 5-hydroxytryptamine recept... 5 47
Sodium-dependent dopamine transporter and Sodium-dependent nor... 6 42
5-hydroxytryptamine receptor 1A and 5-hydroxytryptamine recept... 5 18
5-hydroxytryptamine receptor 1A and 5-hydroxytryptamine recept... 6 45
D(4) dopamine receptor and Alpha-1B adrenergic receptor ligand... 7 27
5-hydroxytryptamine receptor 2C and 5-hydroxytryptamine recept... 2 1
5-hydroxytryptamine receptor 2A ligand AGN-PC-075LXD family 4 4
Nociceptin receptor and Mu-type opioid receptor ligand AGN-PC-... 2 5
5-hydroxytryptamine receptor 2C and 5-hydroxytryptamine recept... 2 0
Sigma non-opioid intracellular receptor 1 ligand 1-[4-[1-adama... 4 23
D(3) dopamine receptor and D(2) dopamine receptor ligand N-[4-... 2 3
Sodium-dependent serotonin transporter and Sodium-dependent no... 3 3
5-hydroxytryptamine receptor 7 ligand 1-[2-(4-nitrophenyl)phen... 1 0
Acetylcholinesterase and Butyrylcholinesterase inhibitor AGN-P... 1 0
Cholinesterase inhibitor 10-[[(1R,9aR)-2,3,4,6,7,8,9,9a-octahy... 1 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00421409 CHEMBL2392023 Bioactive (2R,3R)-2-benzhydryl-N-(2-iodophenyl)-1-azabicyclo[2.2.2]octan-3-amine

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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