CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM13265
Family Name Bifunctional epoxide hydrolase 2 and Cytochrome P450 2C9 inhibitor 1-[4-(dimethylamino)-6-methyl-1,3,5-triazin-2-yl]-N-[[2-(trifluoromethyl)phenyl]methyl]piperidine-4-carboxamide family
No. of Seeds 8 No. of Other Members 6
Family Centroid CFAMM00421457 Functional Category Bioactive
Superfamily Cytochrome P450 2C9 and Bifunctional epoxide hydrolase 2 Binder Superfamily 2
Class Class 4537

Cousin Family NamesSeedsMembers
D(2) dopamine receptor and D(3) dopamine receptor Ligand A-706... 4 20
Oestrogen receptor Ligand 4-benzyl-2,6-diisobutylamino-pyrimid... 5 37
Bifunctional epoxide hydrolase 2 and Cytochrome P450 2C9 inhib... 3 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00421456 CHEMBL2392696 Bioactive 1-[4-methyl-6-(propan-2-ylamino)-1,3,5-triazin-2-yl]-N-[[2-(trifluoromethyl)phenyl]methyl]piperidine-4-carboxamide
CFAMM00421462 CHEMBL2392690 Bioactive N-[[4-fluoro-2-(trifluoromethyl)phenyl]methyl]-1-[4-methyl-6-(methylamino)-1,3,5-triazin-2-yl]piperidine-4-carboxamide
CFAMM00421455 CHEMBL2392697 Bioactive 1-(4-methyl-6-morpholin-4-yl-1,3,5-triazin-2-yl)-N-[[2-(trifluoromethyl)phenyl]methyl]piperidine-4-carboxamide
CFAMM00421461 CHEMBL2392714 Bioactive 1-[4-methyl-6-(methylamino)-1,3,5-triazin-2-yl]-N-[[2-(trifluoromethyl)phenyl]methyl]piperidine-4-carboxamide
CFAMM00421466 CHEMBL2392698 Bioactive 1-[4-(2-methoxyethylamino)-6-methyl-1,3,5-triazin-2-yl]-N-[[2-(trifluoromethyl)phenyl]methyl]piperidine-4-carboxamide
CFAMM00421459 CHEMBL2392693 Bioactive 1-[4-cyclohexyl-6-(methylamino)-1,3,5-triazin-2-yl]-N-[[2-(trifluoromethyl)phenyl]methyl]piperidine-4-carboxamide
CFAMM00421465 CHEMBL2392715 Bioactive 1-[4-ethyl-6-(methylamino)-1,3,5-triazin-2-yl]-N-[[2-(trifluoromethyl)phenyl]methyl]piperidine-4-carboxamide
CFAMM00421457 CHEMBL2392695 Bioactive 1-[4-(dimethylamino)-6-methyl-1,3,5-triazin-2-yl]-N-[[2-(trifluoromethyl)phenyl]methyl]piperidine-4-carboxamide

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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