CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM13276
Family Name Mitogen-activated protein kinase 8 and Mitogen-activated protein kinase 9 inhibitor AGN-PC-08WU8Q family
No. of Seeds 2 No. of Other Members 1
Family Centroid CFAMM00317426 Functional Category Bioactive
Superfamily Serine/threonine-protein kinase mTOR and Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform Binder Superfamily 3
Class Class 1134

Cousin Family NamesSeedsMembers
Transient receptor potential cation channel subfamily V member... 15 457
Adenosine receptor A1 Ligand SLV320 Family 6 79
Aurora kinase B and Aurora kinase C Inhibitor GSK1070916 Family 53 580
Cyclin-dependent kinase 1 and Cyclin-dependent kinase 2 Inhibi... 1 2
C-Jun N-terminal kinase Inhibitor CC-930 Family 2 9
Corticotropin-releasing factor receptor 1 Ligand R121919 Family 26 84
Prostaglandin G/H synthase 2 Inhibitor RWJ-67657 Family 3 33
Vascular endothelial growth factor receptor 1 and Vascular end... 6 23
RAF proto-oncogene serine/threonine-protein kinase Inhibitor L... 219 124
Potassium voltage-gated channel subfamily H member 2 Ligand AZ... 21 42
Tyrosine-protein kinase JAK2 inhibitor AGN-PC-07ZB89 family 6 13
Mitogen-activated protein kinase 8 and Mitogen-activated prote... 2 5
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subun... 4 27
Tyrosine-protein kinase JAK2 inhibitor N-tert-butyl-3-[2-[3-fl... 4 14
Aurora kinase B and Vascular endothelial growth factor recepto... 1 2
Serine/threonine-protein kinase mTOR and Phosphatidylinositol ... 10 3
Activated CDC42 kinase 1 inhibitor N,N-dimethyl-4-[4-[[(2S)-ox... 4 2
Tyrosine-protein kinase JAK1 inhibitor CHEMBL2152398 family 16 1
Serine/threonine-protein kinase SMG1 and Cyclin-dependent kina... 3 1
Tyrosine-protein kinase JAK1 and Non-receptor tyrosine-protein... 7 0
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subun... 3 2
Serine/threonine-protein kinase ATR and Serine/threonine-prote... 8 10
Mitogen-activated protein kinase 8 and Mitogen-activated prote... 4 5
Mitogen-activated protein kinase 8 and Mitogen-activated prote... 2 0
Tyrosine-protein kinase ITK/TSK and Aurora kinase B inhibitor ... 1 1
Cathepsin K and Cathepsin S inhibitor SureCN4138353 family 3 0
G2/mitotic-specific cyclin-B2 and Cyclin-dependent kinase 1 in... 2 1
Neuropeptide Y receptor type 5 ligand 1-methylsulfonyl-N-(2-ph... 4 0
Serine/threonine-protein kinase pim-1 and Glycogen synthase ki... 1 1
Serine/threonine-protein kinase mTOR and Phosphatidylinositol ... 26 0


CFAM Mol ID

External ID

Functional Category

Molecule Name


Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

26194 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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