CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM13286
Family Name Corticosteroid 11-beta-dehydrogenase isozyme 1 and Corticosteroid 11-beta-dehydrogenase isozyme 2 inhibitor 2-(2-chlorophenoxy)-2-methyl-N-(5-methylsulfonyl-2-adamantyl)propanamide family
No. of Seeds 13 No. of Other Members 2
Family Centroid CFAMM00421582 Functional Category Bioactive
Superfamily Corticosteroid 11-beta-dehydrogenase isozyme 1 and Prelamin-A/C Binder Superfamily 4
Class Class 4930

Cousin Family NamesSeedsMembers
Cannabinoid receptor 1 and Cannabinoid receptor 2 ligand N-[(2... 10 12
Corticosteroid 11-beta-dehydrogenase isozyme 1 and Corticoster... 6 22
Corticosteroid 11-beta-dehydrogenase isozyme 1 inhibitor 2-(4-... 3 0
Corticosteroid 11-beta-dehydrogenase isozyme 1 and Corticoster... 2 1
Cathepsin K and Cathepsin L1 inhibitor dipeptidyl nitrile, 16c... 1 0
Corticosteroid 11-beta-dehydrogenase isozyme 1 and Corticoster... 2 0


External ID

Functional Category

Molecule Name

CFAMM00421572 CHEMBL241714 Bioactive 2-(3-chlorophenoxy)-2-methyl-N-(5-methylsulfonyl-2-adamantyl)propanamide
CFAMM00421585 CHEMBL239373 Bioactive AGN-PC-00CS7Y
CFAMM00421578 CHEMBL241717 Bioactive 2-(4-chloro-2-fluorophenoxy)-2-methyl-N-(5-methylsulfonyl-2-adamantyl)propanamide
CFAMM00421584 CHEMBL391652 Bioactive AGN-PC-00AKM6
CFAMM00421577 CHEMBL392913 Bioactive AGN-PC-00CXNI
CFAMM00421583 CHEMBL391653 Bioactive 2-(2,6-dichloro-4-fluorophenoxy)-2-methyl-N-(5-sulfamoyl-2-adamantyl)propanamide
CFAMM00421576 CHEMBL392932 Bioactive AGN-PC-00CHRA
CFAMM00421582 CHEMBL394217 Bioactive 2-(2-chlorophenoxy)-2-methyl-N-(5-methylsulfonyl-2-adamantyl)propanamide
CFAMM00421575 CHEMBL241711 Bioactive N-[5-(2-amino-2-oxoethyl)sulfonyl-2-adamantyl]-2-(2-chloro-4-fluorophenoxy)-2-methylpropanamide
CFAMM00421581 CHEMBL241707 Bioactive AGN-PC-00DIAL
CFAMM00421580 CHEMBL241709 Bioactive 2-(2-chloro-4-fluorophenoxy)-N-(5-ethylsulfonyl-2-adamantyl)-2-methylpropanamide
CFAMM00421573 CHEMBL241716 Bioactive SureCN2824373
CFAMM00421586 CHEMBL399191 Bioactive AGN-PC-00AERY

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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