CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM13289
Family Name Kinesin-like protein KIF11 inhibitor 1-[(5S)-3-(2,5-difluorophenyl)-5-[3-(dimethylamino)propyl]-5-phenyl-4H-pyrazol-1-yl]ethanone family
No. of Seeds 11 No. of Other Members 5
Family Centroid CFAMM00421631 Functional Category Bioactive
Superfamily Kinesin-like protein KIF11 and Retinal dehydrogenase 1 Binder Superfamily
Class Class 4965

Cousin Family NamesSeedsMembers
Kinesin-like protein KIF11 Inhibitor ARRY-520 Family 1 3
Cannabinoid receptor 1 and Cannabinoid receptor 2 ligand AGN-P... 5 20
Cannabinoid receptor 2 and Cannabinoid receptor 1 ligand AGN-P... 2 5
Histamine H3 receptor ligand 2-methyl-6-[4-[2-[(2R)-2-methylpy... 2 4
Amine oxidase [flavin-containing] A and Amine oxidase [flavin-... 3 8


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00421622 CHEMBL239414 Bioactive SureCN4055315
CFAMM00421628 CHEMBL427688 Bioactive 1-[(5S)-3-(2,5-difluorophenyl)-5-phenyl-5-(3-pyrrolidin-1-ylpropyl)-4H-pyrazol-1-yl]ethanone
CFAMM00421621 CHEMBL400042 Bioactive SureCN4258786
CFAMM00421627 CHEMBL240705 Bioactive 1-[(5S)-3-(2,5-difluorophenyl)-5-[3-[2-methoxyethyl(methyl)amino]propyl]-5-phenyl-4H-pyrazol-1-yl]ethanone
CFAMM00421620 CHEMBL400041 Bioactive SureCN4064809
CFAMM00421626 CHEMBL240704 Bioactive 1-[(5S)-3-(2,5-difluorophenyl)-5-[3-[(3S)-3-fluoropyrrolidin-1-yl]propyl]-5-phenyl-4H-pyrazol-1-yl]ethanone
CFAMM00421625 CHEMBL240498 Bioactive SureCN4465141
CFAMM00421631 CHEMBL392148 Bioactive 1-[(5S)-3-(2,5-difluorophenyl)-5-[3-(dimethylamino)propyl]-5-phenyl-4H-pyrazol-1-yl]ethanone
CFAMM00421623 CHEMBL239415 Bioactive SureCN4053510
CFAMM00421616 CHEMBL241754 Bioactive SureCN13629196
CFAMM00421629 CHEMBL398396 Bioactive SureCN4055669

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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