CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM13300
Family Name Bifunctional epoxide hydrolase 2 and RAF proto-oncogene serine/threonine-protein kinase inhibitor 3-[4-[[4-chloro-3-(trifluoromethyl)phenyl]carbamoylamino]cyclohexyl]oxy-N-methylbenzamide family
No. of Seeds 4 No. of Other Members 10
Family Centroid CFAMM00372825 Functional Category Bioactive
Superfamily Huntingtin and Glucagon receptor Binder Superfamily
Class Class 3811

Cousin Family NamesSeedsMembers
5-hydroxytryptamine receptor 1A Ligand (s)-way 100135 Family 94 975
CGMP-inhibited 3',5'-cyclic phosphodiesterase Inhibitor Cilost... 6 202
Substance-K receptor Ligand MEN-14933 Family 13 154
Alpha-1A adrenergic receptor Ligand Upidosin Family 8 46
Melanin-concentrating hormone receptor 1 Ligand N-(1-benzylpip... 9 57
Reverse transcriptase Inhibitor 10-propyl-10h-dibenzo[b,f][1,4... 9 60
Bifunctional epoxide hydrolase 2 inhibitor AGN-PC-04UEH3 family 3 16
Prelamin-A/C and Microtubule-associated protein tau inhibitor ... 1 2
D(3) dopamine receptor and D(4) dopamine receptor ligand N-[4-... 7 9
D(3) dopamine receptor and D(4) dopamine receptor ligand N-[4-... 6 16
Cathepsin L1 and Cathepsin S inhibitor arylaminoethyl amide, 5... 4 5
Sphingosine 1-phosphate receptor 1 ligand 2-methoxy-N-[(4-phen... 2 23
Melanin-concentrating hormone receptor 1 and Melanin-concentra... 9 3
Receptor-type tyrosine-protein kinase FLT3 ligand (3Z)-5-chlor... 1 4
Bifunctional epoxide hydrolase 2 inhibitor 3-[4-[[4-(trifluoro... 5 22
5-hydroxytryptamine receptor 1A and Alpha-1B adrenergic recept... 6 11
Bifunctional epoxide hydrolase 2 inhibitor 8-(2,6-difluorobenz... 4 1
Acyl-CoA desaturase 1 inhibitor AGN-PC-077KJY family 5 4
Acyl-CoA desaturase 1 inhibitor AGN-PC-077KFD family 1 1
Glycogen phosphorylase, liver form inhibitor Glycogen Phosphor... 2 4
Thioredoxin glutathione reductase and Microtubule-associated p... 1 2
Sodium channel protein type 1 subunit alpha and Sodium channel... 3 0
Glucagon receptor ligand 2-chloro-N-[[3-chloro-4-(4-chlorophen... 1 7
Putative NP ZINC09660123 Family 5 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00421682 CHEMBL2397144 Bioactive 3-[4-[[4-chloro-3-(trifluoromethyl)phenyl]carbamoylamino]cyclohexyl]oxybenzoic acid
CFAMM00421685 CHEMBL2397147 Bioactive 4-[4-[[4-chloro-3-(trifluoromethyl)phenyl]carbamoylamino]cyclohexyl]oxybenzoic acid

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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