CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM1331
Family Name 5-hydroxytryptamine receptor 3A and 5-hydroxytryptamine receptor 3B ligand SureCN9269649 family
No. of Seeds 1 No. of Other Members 7
Family Centroid CFAMM00322232 Functional Category Bioactive with Natural Product
Superfamily 5-hydroxytryptamine receptor 3B and 5-hydroxytryptamine receptor 3A Binder Superfamily 3
Class Class 2101

Cousin Family NamesSeedsMembers
Cytochrome P450 3A4 Inhibitor Clotrimazole Family 16 145
Alpha-2 adrenergic receptor Ligand Dexmedetomidine Family 32 639
Histamine H1 receptor Ligand Emedastine Family 5 115
Histamine H1 receptor Ligand Mizolastine Family 14 603
Metabotropic glutamate receptor 5 Ligand ADX-48621 Family 15 444
C-X-C chemokine receptor type 4 Ligand AMD-070 Family 12 800
Telomerase protein component 1 Inhibitor GRN163L Family 5 29
Vascular endothelial growth factor Inhibitor PTC299 Family 6 145
Vascular endothelial growth factor receptor 2 Ligand XL999 Family 11 87
Steroid 17-alpha-hydroxylase/17,20 lyase and Aromatase Inhibit... 18 109
Cytochrome P450 11B1, mitochondrial Inhibitor 1-(4-cyanobenzyl... 14 13
Methionine aminopeptidase 2 Inhibitor 2-(pyridin-2-yl)-1h-benz... 6 19
Alpha-1A adrenergic receptor and Alpha-1B adrenergic receptor ... 5 7
Metabotropic glutamate receptor 5 Ligand 3-(4-pyridin-2-yl-imi... 6 5
Cytochrome P450 11B1, mitochondrial Inhibitor 1-(4-aminobenzyl... 3 6
Delta-type opioid receptor and Kappa-type opioid receptor Liga... 5 45
Farnesyl pyrophosphate synthase Inhibitor [2-(benzoimidazol-1-... 2 16
Potassium voltage-gated channel subfamily H member 2 Ligand AZ... 21 42
Cytochrome P450 11B1, mitochondrial Inhibitor 1-(4-bromobenzyl... 3 0
Histamine H3 receptor Ligand 4-(2-(phenylamino)ethyl)-1h-imida... 5 16
Nitric oxide synthase, inducible and Nitric oxide synthase, br... 1 4
5-hydroxytryptamine receptor 3A and 5-hydroxytryptamine recept... 2 0
5-hydroxytryptamine receptor 3A and 5-hydroxytryptamine recept... 1 0
5-hydroxytryptamine receptor 3A and 5-hydroxytryptamine recept... 2 1
5-hydroxytryptamine receptor 3A and 5-hydroxytryptamine recept... 7 4
Gamma-aminobutyric acid receptor subunit pi and GABA theta sub... 7 10
Nociceptin receptor and Kappa-type opioid receptor ligand 1-[1... 4 4
D(2) dopamine receptor and 5-hydroxytryptamine receptor 1A lig... 2 2
Tripeptidyl-peptidase 2 inhibitor (2S)-2-amino-1-[(2S)-5-chlor... 1 0
Cyclin-dependent kinase 2 inhibitor SureCN3549598 family 3 1
Pyruvate kinase PKM inhibitor 2-(benzimidazol-1-ylmethyl)-6-me... 1 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00322232 CHEMBL1160921 Bioactive SureCN9269649

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

26240 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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