CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM13315
Family Name Glutamate receptor ionotropic, NMDA 1 and Glutamate receptor ionotropic, NMDA 2A ligand N,N'-bis[6-(2,2-diphenylethylamino)hexyl]dodecane-1,12-diamine family
No. of Seeds 1 No. of Other Members 5
Family Centroid CFAMM00421762 Functional Category Bioactive
Superfamily C-C chemokine receptor type 5 and Glutamate receptor ionotropic, NMDA 1 Binder Superfamily
Class Class 115

Cousin Family NamesSeedsMembers
Beta adrenergic receptor Ligand Bethanidine Family 2 22
Alpha-1B adrenergic receptor ligand phenethylamine derivative ... 12 283
5-hydroxytryptamine 2 receptor Ligand tricyclic antidepressant... 29 680
Voltage-dependent T-type calcium channel subunit alpha-1H liga... 10 397
Histamine H1 receptor ligand piperazine derivative Cyclizine F... 16 140
Noradrenergic re-uptake Inhibitor Phentermine Family 2 11
Squalene monooxygenase Inhibitor Naftifine Family 8 32
Noradrenergic re-uptake Inhibitor Protriptyline Family 3 25
Muscarinic acetylcholine receptor M3 Ligand Diphemanil Methyls... 22 45
Noradrenergic re-uptake Inhibitor Maprotiline Family 6 33
Serotonin re-uptake Inhibitor Dexfenfluramine Family 6 31
C-X-C chemokine receptor type 4 Ligand AMD-3100 Family 3 6
Glutamate receptor AMPA subtype and Noradrenaline uptake Ligan... 9 17
Dipeptidyl peptidase 4 Inhibitor 1-biphenyl-2-ylmethanamine Fa... 2 23
Beta-secretase 1 Inhibitor 4-(4-fluorobenzyl)piperidine Family 2 4
D(2) dopamine receptor and D(3) dopamine receptor Ligand (-)-3... 15 19
Adenosine receptor A3 and Glutamate receptor ionotropic, NMDA ... 4 30
Calcium-activated potassium channel subunit alpha-1 Ligand N-m... 2 10
Amine oxidase [flavin-containing] A Inhibitor 1-(2-naphthyl)-2... 4 4
Sodium-dependent serotonin transporter Inhibitor 1-(2-(naphtha... 5 2
Sodium-dependent dopamine transporter and Sodium-dependent nor... 28 71
5-hydroxytryptamine receptor 1A and 5-hydroxytryptamine recept... 6 1
Alpha-2A adrenergic receptor and Alpha-2B adrenergic receptor ... 17 9
Alpha-2A adrenergic receptor and Alpha-2B adrenergic receptor ... 4 1
Substance-P receptor ligand AGN-PC-03NGZZ family 1 1
Sodium-dependent serotonin transporter and Sodium-dependent no... 3 3
Histamine H3 receptor ligand 4-[6-(2-pyrrolidin-3-ylethyl)naph... 1 1


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00421762 CHEMBL2398522 Bioactive N,N'-bis[6-(2,2-diphenylethylamino)hexyl]dodecane-1,12-diamine

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

27698 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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