CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM13328
Family Name P2Y purinoceptor 1 inhibitor N-[2-(2-tert-butylphenoxy)pyridin-3-yl]-5-phenyl-4-(trifluoromethyl)-1,3-thiazol-2-amine family
No. of Seeds 6 No. of Other Members 3
Family Centroid CFAMM00421824 Functional Category Bioactive
Superfamily P2Y purinoceptor 1 Binder Superfamily 2
Class Class 985

Cousin Family NamesSeedsMembers
RAF proto-oncogene serine/threonine-protein kinase inhibitor A... 8 3
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10... 5 6
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subun... 1 1
P2Y purinoceptor 1 inhibitor N-[2-(2-tert-butylphenoxy)pyridin... 2 19
Glucokinase inhibitor 4-methyl-N-[3-phenylmethoxy-5-(pyridin-2... 1 8


External ID

Functional Category

Molecule Name

CFAMM00421828 CHEMBL2401856 Bioactive N-[2-(2-tert-butylphenoxy)pyridin-3-yl]-5-(4-methylphenyl)-4-(trifluoromethyl)-1,3-thiazol-2-amine
CFAMM00421824 CHEMBL2401800 Bioactive N-[2-(2-tert-butylphenoxy)pyridin-3-yl]-5-phenyl-4-(trifluoromethyl)-1,3-thiazol-2-amine
CFAMM00421831 CHEMBL2401859 Bioactive N-[2-(2-tert-butylphenoxy)pyridin-3-yl]-5-(4-methoxyphenyl)-4-(trifluoromethyl)-1,3-thiazol-2-amine
CFAMM00421823 CHEMBL2401804 Bioactive ethyl 2-[[2-(2-tert-butylphenoxy)pyridin-3-yl]amino]-4-(trifluoromethyl)-1,3-thiazole-5-carboxylate
CFAMM00421830 CHEMBL2401858 Bioactive N-[2-(2-tert-butylphenoxy)pyridin-3-yl]-5-(3-methoxyphenyl)-4-(trifluoromethyl)-1,3-thiazol-2-amine
CFAMM00421829 CHEMBL2401857 Bioactive N-[2-(2-tert-butylphenoxy)pyridin-3-yl]-5-(2-fluorophenyl)-4-(trifluoromethyl)-1,3-thiazol-2-amine

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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