CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM13364
Family Name Leucine-rich repeat serine/threonine-protein kinase 2 and Vascular endothelial growth factor receptor 2 ligand N-[(3Z)-3-[[5-(morpholine-4-carbonyl)-1,4,6,7-tetrahydropyrrolo[3,2-c]pyridin-2-yl]methylidene]-2-oxo-1H-indol-5-yl]acetamide family
No. of Seeds 3 No. of Other Members 3
Family Centroid CFAMM00415248 Functional Category Bioactive
Superfamily Hormone-sensitive lipase and Vascular endothelial growth factor receptor 2 Binder Superfamily
Class Class 1196

Cousin Family NamesSeedsMembers
Receptor-type tyrosine-protein kinase FLT3 inhibitor indoline ... 4 151
5-hydroxytryptamine receptor 1B and 5-hydroxytryptamine recept... 14 2769
Lethal factor Inhibitor GM6001 Family 50 435
Cholecystokinin receptor type A Ligand VL-0395 Family 12 117
cAMP-specific 3',5'-cyclic phosphodiesterase 4A and cAMP-speci... 3 29
Acetylcholinesterase and Cholinesterase Inhibitor 3-(2-diethyl... 12 160
MAP kinase-activated protein kinase 2 and Mitogen-activated pr... 5 2
Cellular tumor antigen p53 inhibitor CHEMBL1418224 family 1 62
Survival motor neuron protein and Nonstructural protein 1 inhi... 1 18
Somatostatin receptor type 4 ligand methyl 5-(diaminomethylide... 2 34
5-hydroxytryptamine receptor 1A and D(2) dopamine receptor lig... 3 2
Adenosine receptor A2b and Adenosine receptor A2a ligand N-(4-... 2 14
High affinity nerve growth factor receptor and BDNF/NT-3 growt... 4 3
Oxytocin receptor ligand (3R,6R)-3-(2,3-dihydro-1H-inden-2-yl)... 20 2
Serine/threonine-protein kinase Chk1 inhibitor SureCN5547533 f... 3 2
RAC-beta serine/threonine-protein kinase and 3-phosphoinositid... 11 4
Leucine-rich repeat serine/threonine-protein kinase 2 and Plat... 1 0
Phospholipase D1 and Phospholipase D2 inhibitor SureCN10311349... 2 14
Tyrosine-protein kinase Yes and Proto-oncogene tyrosine-protei... 7 18
Histamine H3 receptor ligand SureCN3542210 family 1 0
Neutrophil collagenase and Stromelysin-1 inhibitor (3R)-N-hydr... 1 6


CFAM Mol ID

External ID

Functional Category

Molecule Name


Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

45292 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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