CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM13365
Family Name Leucine-rich repeat serine/threonine-protein kinase 2 and Platelet-derived growth factor receptor alpha ligand (3Z)-3-[(5-acetyl-1,4,6,7-tetrahydropyrrolo[3,2-c]pyridin-2-yl)methylidene]-5-nitro-1H-indol-2-one family
No. of Seeds 1 No. of Other Members 0
Family Centroid CFAMM00414414 Functional Category Bioactive
Superfamily Hormone-sensitive lipase and Vascular endothelial growth factor receptor 2 Binder Superfamily
Class Class 1196

Cousin Family NamesSeedsMembers
Receptor-type tyrosine-protein kinase FLT3 inhibitor indoline ... 4 151
5-hydroxytryptamine receptor 1B and 5-hydroxytryptamine recept... 14 2769
Hepatocyte growth factor receptor Ligand Arq 197 Family 10 400
Glycogen synthase kinase-3 beta and Protein kinase C beta type... 5 53
Receptor-type tyrosine-protein kinase FLT3 Inhibitor SU5614 Fa... 4 36
Fibroblast growth factor receptor 1 and Aurora kinase B Inhibi... 4 51
Poly [ADP-ribose] polymerase 1 Inhibitor AG-14699 Family 13 179
Growth hormone receptor Ligand EP-51216 Family 34 390
Histone deacetylase 1 Inhibitor Panobinostat Family 5 93
Lethal factor Inhibitor GM6001 Family 50 435
Cyclin-dependent kinase 5 Inhibitor 9-nitropaullone Family 2 13
Poly [ADP-ribose] polymerase 1 Inhibitor 1,7,8,9-tetrahydro-1,... 19 64
Cholecystokinin receptor type A Ligand VL-0395 Family 12 117
Gamma-aminobutyric acid receptor subunit alpha-1 and Gamma-ami... 12 72
Vasopressin V2 receptor Ligand YM-35278 Family 33 38
Acetylcholinesterase and Cholinesterase Inhibitor 3-(2-diethyl... 12 160
Histone deacetylase Inhibitor ST-5732 Family 8 6
Translocator protein inhibitor AGN-PC-07RE6S family 1 0
Cellular tumor antigen p53 and Beta-lactamase inhibitor CHEMBL... 1 36
D(2) dopamine receptor and 5-hydroxytryptamine receptor 1A lig... 5 8
Translocator protein inhibitor AGN-PC-08WI0V family 1 0
5-hydroxytryptamine receptor 1A and D(2) dopamine receptor lig... 3 2
Histone deacetylase 6 and Histone deacetylase 1 inhibitor 4-[(... 3 5
High affinity nerve growth factor receptor and BDNF/NT-3 growt... 4 3
Serine/threonine-protein kinase Chk1 inhibitor SureCN5547533 f... 3 2
RAC-beta serine/threonine-protein kinase and 3-phosphoinositid... 11 4
Disintegrin and metalloproteinase domain-containing protein 17... 7 9
Gonadotropin-releasing hormone receptor ligand SureCN7899418 f... 12 4
Leucine-rich repeat serine/threonine-protein kinase 2 and Vasc... 3 3
Somatostatin receptor type 1 and Somatostatin receptor type 2 ... 2 18
Somatostatin receptor type 1 and Somatostatin receptor type 2 ... 3 5
Tyrosine-protein kinase Yes and Proto-oncogene tyrosine-protei... 7 18
Neuromedin-B receptor and Gastrin-releasing peptide receptor l... 6 4
Interstitial collagenase and Matrix metalloproteinase-9 inhibi... 1 5


CFAM Mol ID

External ID

Functional Category

Molecule Name


Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

22645 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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