CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM13369
Family Name Metabotropic glutamate receptor 5 ligand (2-methylcyclopropyl)-[2-(2-phenylethynyl)-6,7-dihydro-4H-[1,3]thiazolo[5,4-c]pyridin-5-yl]methanone family
No. of Seeds 3 No. of Other Members 6
Family Centroid CFAMM00422044 Functional Category Bioactive
Superfamily Histamine H3 receptor Ligand ST-1025 Superfamily
Class Class 2432

Cousin Family NamesSeedsMembers
Dipeptidyl peptidase 4 and Dipeptidyl peptidase 8 inhibitor th... 1 3
Metabotropic glutamate receptor 5 ligand [2-(2-phenylethynyl)-... 2 36
Metabotropic glutamate receptor 5 ligand (3-chlorophenyl)-[2-(... 1 4
Metabotropic glutamate receptor 5 ligand 5-methyl-2-(2-phenyle... 2 5
Metabotropic glutamate receptor 5 ligand 2-(2-pyridin-3-ylethy... 1 2


External ID

Functional Category

Molecule Name

CFAMM00422044 CHEMBL2403683 Bioactive (2-methylcyclopropyl)-[2-(2-phenylethynyl)-6,7-dihydro-4H-[1,3]thiazolo[5,4-c]pyridin-5-yl]methanone
CFAMM00422043 CHEMBL2403684 Bioactive [2-(2-phenylethynyl)-6,7-dihydro-4H-[1,3]thiazolo[5,4-c]pyridin-5-yl]-spiro[2.3]hexan-2-ylmethanone
CFAMM00422048 CHEMBL2403690 Bioactive (3,3-difluorocyclobutyl)-[2-[2-(3-fluorophenyl)ethynyl]-6,7-dihydro-4H-[1,3]thiazolo[5,4-c]pyridin-5-yl]methanone

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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