CFam Chemical Families Database
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Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM13376
Family Name Growth hormone secretagogue receptor type 1 ligand N-[(1R)-2-(1H-indol-3-yl)-1-[4-[(4-methoxyphenyl)methyl]-5-(2-phenylethyl)-1,5-dihydro-1,2,4-triazol-3-yl]ethyl]piperidine-4-carboxamide family
No. of Seeds 3 No. of Other Members 2
Family Centroid CFAMM00422077 Functional Category Bioactive
Superfamily Growth hormone secretagogue receptor type 1 and Protein Mdm4 Binder Superfamily
Class Class 851

Cousin Family NamesSeedsMembers
Melatonin receptor type 1A Ligand Melatonin Family 20 988
cGMP-specific 3',5'-cyclic phosphodiesterase inhibitor indole... 28 2712
Somatostatin receptor type 2 ligand octapeptide Lanreotide Family 93 156
ostatin receptor 5 Ligand Pasireotide Diaspartate Family 11 151
Calcium-activated potassium channel subunit alpha-1 Ligand AVE... 3 284
Protein kinase C theta type Inhibitor 4-(1h-indol-5-yloxy)-5-s... 21 194
Delta-type opioid receptor and Gastrin/cholecystokinin type B ... 19 0
5-hydroxytryptamine receptor 2C Ligand N-(6-phenoxypyridin-3-y... 9 69
Reverse transcriptase Inhibitor Atevirdine Family 4 55
Delta-type opioid receptor and Mu-type opioid receptor Ligand ... 18 72
5-hydroxytryptamine receptor 1D and 5-hydroxytryptamine recept... 14 48
Sodium channel protein type 10 subunit alpha and Sodium channe... 3 22
Cellular tumor antigen p53 and DNA polymerase beta inhibitor C... 1 15
Somatostatin receptor type 2 ligand tert-butyl (2S)-6-amino-2-... 2 15
Growth hormone secretagogue receptor type 1 ligand 2-amino-N-[... 3 3
Sodium-dependent serotonin transporter and 5-hydroxytryptamine... 2 1
Histone deacetylase 1 and Potassium voltage-gated channel subf... 1 0
Substance-P receptor ligand (3R)-4-[3,5-bis(trifluoromethyl)be... 2 3
Substance-P receptor ligand 1-[4-(2-methoxyphenyl)piperazin-1-... 11 12
Growth hormone secretagogue receptor type 1 ligand SureCN36800... 14 42
Growth hormone secretagogue receptor type 1 ligand SureCN36380... 6 0
5-hydroxytryptamine receptor 1D and 5-hydroxytryptamine recept... 8 13
Substance-P receptor ligand N-[(2R)-1-[acetyl-[(2-chlorophenyl... 2 2
Cathepsin K inhibitor N-[(2S)-4-methyl-1-[2-[4-(2-methylpropox... 4 0
Neuromedin-B receptor and Gastrin-releasing peptide receptor l... 4 1
Substance-P receptor ligand AGN-PC-00FIT5 family 3 11
Substance-P receptor ligand AGN-PC-0D60L0 family 2 7
cGMP-specific 3',5'-cyclic phosphodiesterase inhibitor CHEMBL4... 6 2
Cholecystokinin receptor type A ligand AGN-PC-077KXF family 2 0
Bombesin receptor subtype-3 ligand 2-[[(E)-furan-2-ylmethylide... 2 4


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00422077 CHEMBL240509 Bioactive N-[(1R)-2-(1H-indol-3-yl)-1-[4-[(4-methoxyphenyl)methyl]-5-(2-phenylethyl)-1,5-dihydro-1,2,4-triazol-3-yl]ethyl]piperidine-4-carboxamide
CFAMM00422075 CHEMBL391588 Bioactive N-[(1R)-1-[4-[(2,4-dimethoxyphenyl)methyl]-5-(2-phenylethyl)-1,5-dihydro-1,2,4-triazol-3-yl]-2-(1H-indol-3-yl)ethyl]piperidine-4-carboxamide
CFAMM00422073 CHEMBL397593 Bioactive N-[(1R)-2-(1H-indol-3-yl)-1-[4-[(4-methoxyphenyl)methyl]-5-(2-phenylethyl)-1,5-dihydro-1,2,4-triazol-3-yl]ethyl]oxane-4-carboxamide

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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