CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM13385
Family Name Carbonic anhydrase 2 and Carbonic anhydrase 5A, mitochondrial inhibitor AGN-PC-0415FR family
No. of Seeds 4 No. of Other Members 5
Family Centroid CFAMM00422138 Functional Category Bioactive
Superfamily Estrogen receptor beta Ligand Thiogenistein Superfamily
Class Class 785

Cousin Family NamesSeedsMembers
Sphingosine kinase 2 Inhibitor Phenoxodiol Family 24 682
NAD-dependent protein deacetylase sirtuin-1 Inhibitor SRT501 F... 19 88
Steryl-sulfatase Inhibitor Stx 64 Family 7 160
Platelet-activating factor receptor Ligand L-652731 Family 5 116
Abelson tyrosine-protein kinase 2 Inhibitor 3'',5''-dimethoxy-... 3 9
Carbonic anhydrase 9 and Carbonic anhydrase 12 Inhibitor Ethox... 12 80
Kappa-type opioid receptor Ligand Anisocoumarin H Family 3 5
Androgen receptor Ligand 2-methoxy-4-(o-tolyloxy)benzonitrile ... 5 12
Prostaglandin G/H synthase 1 and Prostaglandin G/H synthase 2 ... 2 12
Indoleamine 2,3-dioxygenase 1 Inhibitor 4-methoxybenzenemethan... 2 26
Androgen receptor Ligand Palodesangren E Family 12 43
Carbonic anhydrase 2 and Carbonic anhydrase 5A, mitochondrial ... 1 0
Carbonic anhydrase 2 and Carbonic anhydrase 5A, mitochondrial ... 3 5
Carbonic anhydrase 2 and Carbonic anhydrase 5A, mitochondrial ... 3 2
Amine oxidase [flavin-containing] A inhibitor AGN-PC-00LZQK fa... 1 24
Toluenes Metabolite p-Cresol sulfate Family 1 5
Benzyloxycarbonyls Metabolite 4-Methoxybenzyl formate Family 1 7
Benzene and Substituted Derivatives Metabolite 1,3,5-Trimethox... 2 17


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00422132 CHEMBL2407307 Bioactive (2,2-dioxo-3,4-dihydro-1,2$l^{6}-benzoxathiin-7-yl) methanesulfonate
CFAMM00422138 CHEMBL2407312 Bioactive AGN-PC-0415FR
CFAMM00422131 CHEMBL2407309 Bioactive (2,2-dioxo-1,2$l^{6}-benzoxathiin-7-yl) methanesulfonate
CFAMM00422137 CHEMBL2407311 Bioactive 7-methoxy-1,2$l^{6}-benzoxathiine 2,2-dioxide

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

27272 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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