CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM13395
Family Name Mitogen-activated protein kinase kinase kinase 7 and TGF-beta-activated kinase 1 and MAP3K7-binding protein 1 inhibitor 1-[4-[4-[7-amino-2-(1,2,3-benzothiadiazol-7-yl)furo[2,3-c]pyridin-4-yl]pyrazol-1-yl]piperidin-1-yl]ethanone family
No. of Seeds 3 No. of Other Members 14
Family Centroid CFAMM00422198 Functional Category Bioactive
Superfamily Hepatocyte growth factor receptor and Mitogen-activated protein kinase kinase kinase 7 Binder Superfamily
Class Class 918

Cousin Family NamesSeedsMembers
Metabotropic glutamate receptor 1 Ligand PF-1913539 Family 130 817
Serine/threonine-protein kinase mTOR Inhibitor INK128 Family 2 15
MK-3328 family 2 32
Mitogen-activated protein kinase 14 Inhibitor CP-808844 Family 39 43
Receptor-type tyrosine-protein kinase FLT3 and Hepatocyte grow... 7 56
Adenosine receptor A2a and Adenosine receptor A1 ligand AGN-PC... 2 1
Fatty-acid amide hydrolase 1 inhibitor 3-[(3R)-1-[4-(1-benzofu... 4 4
Hepatocyte growth factor receptor ligand 2-[2-amino-5-(1-piper... 4 0
RAC-alpha serine/threonine-protein kinase and RAC-beta serine/... 15 1


External ID

Functional Category

Molecule Name

CFAMM00422199 CHEMBL2407758 Bioactive 1-[4-[4-[7-amino-2-(1,3-benzothiazol-7-yl)furo[2,3-c]pyridin-4-yl]pyrazol-1-yl]piperidin-1-yl]ethanone
CFAMM00422192 CHEMBL2408610 Bioactive 4-[4-[7-amino-2-(1,2,3-benzothiadiazol-7-yl)furo[2,3-c]pyridin-4-yl]pyrazol-1-yl]cyclohexan-1-ol
CFAMM00422198 CHEMBL2407759 Bioactive 1-[4-[4-[7-amino-2-(1,2,3-benzothiadiazol-7-yl)furo[2,3-c]pyridin-4-yl]pyrazol-1-yl]piperidin-1-yl]ethanone

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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