CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM13396
Family Name Phosphatidylinositol 4-kinase beta inhibitor (4E)-2-fluoro-4-[2-methyl-8-[(3-methylsulfonylphenyl)methylamino]-7H-imidazo[1,2-a]pyrazin-3-ylidene]cyclohexa-2,5-dien-1-one family
No. of Seeds 1 No. of Other Members 3
Family Centroid CFAMM00422202 Functional Category Bioactive
Superfamily Prostaglandin G/H synthase 1 and Prostaglandin G/H synthase 2 Inhibitor Cimicoxib Superfamily
Class Class 1249

Cousin Family NamesSeedsMembers
Histamine H1 receptor Ligand Astemizole Family 7 240
Tyrosine kinase Inhibitor PKI166 Family 17 198
Oestrogen receptor and Estrogen receptor beta Ligand 4-(2-phen... 2 9
Glycogen synthase kinase-3 beta and Mitogen-activated protein ... 8 8
Reverse transcriptase Inhibitor UK-129485 Family 23 221
Delta-type opioid receptor and Mu-type opioid receptor Ligand ... 13 15
Proto-oncogene tyrosine-protein kinase Src and Cyclin-dependen... 2 1
D(3) dopamine receptor and D(2) dopamine receptor ligand SureC... 5 4
Hepatocyte growth factor receptor ligand 4-[(6-phenyl-[1,2,4]t... 3 6
Lysine--tRNA ligase inhibitor 4-[[[2-(2-piperazin-1-ylpyridin-... 2 1
Tyrosine-protein kinase Lck inhibitor 3-[[2-(benzimidazol-1-yl... 2 0
Oxysterols receptor LXR-alpha and Oxysterols receptor LXR-beta... 13 8
Oxysterols receptor LXR-alpha and Oxysterols receptor LXR-beta... 7 4


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00422202 CHEMBL2407818 Bioactive (4E)-2-fluoro-4-[2-methyl-8-[(3-methylsulfonylphenyl)methylamino]-7H-imidazo[1,2-a]pyrazin-3-ylidene]cyclohexa-2,5-dien-1-one

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

26855 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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