CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM13400
Family Name Serine/threonine-protein kinase PLK4 inhibitor (3E)-3-[[3-[(E)-2-[4-[(dimethylamino)methyl]phenyl]ethenyl]-1H-indazol-6-yl]methylidene]-5-methoxy-1H-indol-2-one family
No. of Seeds 1 No. of Other Members 1
Family Centroid CFAMM00422212 Functional Category Bioactive
Superfamily Serine/threonine-protein kinase PLK4 and cAMP Binder Superfamily
Class Class 842

Cousin Family NamesSeedsMembers
Serine/threonine-protein kinase Chk1 Inhibitor A-432411 Family 4 70
5-hydroxytryptamine receptor 2C Ligand N-(6-phenoxypyridin-3-y... 9 69
Vasopressin V1a receptor and Vasopressin V2 receptor ligand (3... 4 41
Cyclin-dependent kinase 4 and G1/S-specific cyclin-D1 inhibito... 19 40
Serine/threonine-protein kinase RIO2 and Serine/threonine-prot... 19 10
Serine/threonine-protein kinase RIO2 and Serine/threonine-prot... 12 13
Smoothened homolog and Mitogen-activated protein kinase 14 inh... 3 0
Serine/threonine-protein kinase PLK4 inhibitor (3E)-5-methoxy-... 4 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00422212 CHEMBL2407898 Bioactive (3E)-3-[[3-[(E)-2-[4-[(dimethylamino)methyl]phenyl]ethenyl]-1H-indazol-6-yl]methylidene]-5-methoxy-1H-indol-2-one

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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