CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM13404
Family Name Poly [ADP-ribose] polymerase 1 inhibitor N-ethyl-4-[4-[(8-methoxy-2-methyl-3-oxo-4H-1,4-benzoxazin-6-yl)methyl]piperazin-1-yl]-3-methylbenzamide family
No. of Seeds 1 No. of Other Members 0
Family Centroid CFAMM00422219 Functional Category Bioactive
Superfamily Melanin-concentrating hormone receptor 1 and D(2) dopamine receptor Binder Superfamily
Class Class 1677

Cousin Family NamesSeedsMembers
5-hydroxytryptamine receptor 1A Ligand (s)-way 100135 Family 94 975
Alpha-2C adrenergic receptor Ligand ARC239 Family 15 23
Alpha-1A adrenergic receptor Ligand Upidosin Family 8 46
Leukotriene A-4 hydrolase Inhibitor N5-[4-(2-oxo-3-phenylpropo... 1 61
Galanin receptor type 1 and Galanin receptor type 2 Ligand Gal... 55 132
D(2) dopamine receptor ligand 7-[4-[4-(2-ethoxyphenyl)piperazi... 12 14
5-hydroxytryptamine receptor 1A and D(2) dopamine receptor lig... 49 8
D(4) dopamine receptor and D(2) dopamine receptor ligand SureC... 4 3
5-hydroxytryptamine receptor 1A and D(2) dopamine receptor lig... 5 2
Growth hormone secretagogue receptor type 1 ligand (2R)-N-(1-b... 11 4
Poly [ADP-ribose] polymerase 1 inhibitor 3-chloro-N-cyclopropy... 1 2
Serine/threonine-protein kinase Chk1 inhibitor 2-[9-(4-amino-3... 5 2


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00422219 CHEMBL2407987 Bioactive N-ethyl-4-[4-[(8-methoxy-2-methyl-3-oxo-4H-1,4-benzoxazin-6-yl)methyl]piperazin-1-yl]-3-methylbenzamide

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

24317 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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