CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM13405
Family Name Poly [ADP-ribose] polymerase 1 inhibitor 6-[[4-(4-chlorophenyl)-3,6-dihydro-2H-pyridin-1-yl]methyl]-2-methyl-4H-1,4-benzoxazin-3-one family
No. of Seeds 1 No. of Other Members 0
Family Centroid CFAMM00422221 Functional Category Bioactive
Superfamily Acyl-CoA desaturase and Adenosine receptor A1 Binder Superfamily
Class Class 4476

Cousin Family NamesSeedsMembers
D(2) dopamine receptor ligand phenylpiperazine derivative Arip... 3 53
Beta-2 adrenergic receptor Ligand Olodaterol Family 16 27
5-hydroxytryptamine receptor 1A Ligand (s)-way 100135 Family 94 975
Muscarinic acetylcholine receptor M1 Ligand AC-260584 Family 4 36
C-C chemokine receptor type 1 Ligand BX-471 Family 10 67
Alpha-1A adrenergic receptor and Alpha-1B adrenergic receptor ... 6 23
Alpha-1A adrenergic receptor and D(2) dopamine receptor Ligand... 5 49
Leukotriene A-4 hydrolase Inhibitor N5-[4-(2-oxo-3-phenylpropo... 1 61
Macrophage migration inhibitory factor Inhibitor 3-benzyl-5-me... 10 42
Bifunctional epoxide hydrolase 2 Inhibitor 1-(3-(3-morpholinop... 24 102
5-hydroxytryptamine receptor 1A and Sodium-dependent dopamine ... 8 41
Galanin receptor type 1 and Galanin receptor type 2 Ligand Gal... 55 132
D(4) dopamine receptor ligand AGN-PC-004XJQ family 2 1
D(2) dopamine receptor ligand 7-[4-[4-(2-ethoxyphenyl)piperazi... 12 14
D(3) dopamine receptor and D(2) dopamine receptor ligand (E)-N... 2 2
D(4) dopamine receptor and D(2) dopamine receptor ligand SureC... 4 3
D(4) dopamine receptor and D(3) dopamine receptor ligand SureC... 5 0
D(3) dopamine receptor and D(4) dopamine receptor ligand N-[4-... 6 16
Potassium voltage-gated channel subfamily H member 2 and Melan... 9 4
Androgen receptor ligand (2R)-2-ethyl-1-(2,2,2-trifluoroethyl)... 32 6
C-C chemokine receptor type 1 ligand SureCN3164653 family 2 1
Translocator protein inhibitor AGN-PC-00CH84 family 3 0
Receptor-type tyrosine-protein kinase FLT3 ligand (3Z)-5-chlor... 1 4
5-hydroxytryptamine receptor 1A and Alpha-1B adrenergic recept... 6 11
C-C chemokine receptor type 1 ligand N-[2-[(2S)-3-(5-chlorospi... 4 0
Poly [ADP-ribose] polymerase 1 inhibitor 3-chloro-N-cyclopropy... 1 2
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subun... 5 0
Glutamate receptor ionotropic, NMDA 2B and Potassium voltage-g... 2 1
Urotensin-2 receptor and Kappa-type opioid receptor ligand 6,7... 2 0
Urotensin-2 receptor and Cytochrome P450 3A4 ligand 5-chloro-3... 2 1
5-hydroxytryptamine receptor 1B and 5-hydroxytryptamine recept... 2 0
Bifunctional epoxide hydrolase 2 inhibitor AGN-PC-00RZQT family 3 4
Acyl-CoA desaturase and Acyl-CoA desaturase 1 inhibitor SureCN... 1 0
Alpha-1A adrenergic receptor and Alpha-1B adrenergic receptor ... 4 0
P2X purinoceptor 7 inhibitor SureCN3722920 family 4 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00422221 CHEMBL2408002 Bioactive 6-[[4-(4-chlorophenyl)-3,6-dihydro-2H-pyridin-1-yl]methyl]-2-methyl-4H-1,4-benzoxazin-3-one

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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