CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM13408
Family Name Histone deacetylase 2 and Histone deacetylase 8 inhibitor AC1LDAG2 family
No. of Seeds 2 No. of Other Members 2
Family Centroid CFAMM00422227 Functional Category Bioactive with Natural Product
Superfamily Acetylcholinesterase and Histone deacetylase 8 Binder Superfamily
Class Class 4370

Cousin Family NamesSeedsMembers
Lipoprotein lipase Inhibitor Gemfibrozil Family 1 28
Cyclooxygenase Inhibitor Fenoprofen Family 4 1077
Cyclooxygenase inhibitor salicylate derivative Aspirin family 3 234
Vitamin K epoxide reductase complex subunit 1 Inhibitor Warfar... 9 508
Tyrosinase Inhibitor Monobenzone Family 6 197
Vitamin K-dependent gamma-carboxylase Inhibitor Anisindione Fa... 3 243
D-alanyl-D-alanine carboxypeptidase Inhibitor B-lactams Family 59 1364
Aldehyde oxidase Inhibitor Isovanillin Family 6 429
Ipriflavone family 62 2480
Rotenone family 16 107
Danthron family 11 141
Agrimophol family 10 22
Leukotriene B4 receptor 1 Ligand LY293111 Family 24 79
Multidrug resistance protein Inhibitor Curcumin I Family 19 278
Phospholipase A2 Inhibitor P-anisic Acid Family 2 178
Steryl-sulfatase Inhibitor Sulfamic Acid 4-(3-methoxy-benzoyl)... 5 24
Steryl-sulfatase Inhibitor Sulfamic Acid 2-nonyl-4-oxo-4h-chro... 4 68
Oestrogen receptor and Estrogen receptor beta Ligand 7-chloro-... 2 27
Cannabinoid receptor 1 and Cannabinoid receptor 2 Ligand 4-(1,... 3 31
Amine oxidase [flavin-containing] B Inhibitor (s)(+)-7-fluoro-... 11 11
Carbonic anhydrase 1 and Carbonic anhydrase 2 Inhibitor 6-meth... 2 36
Aromatase Inhibitor 3,4-bis(3,4-dimethoxyphenyl)furan-2(5h)-on... 4 86
Amine oxidase [flavin-containing] B Inhibitor 4-oxo-4h-chromen... 2 3
Gamma-aminobutyric acid receptor subunit alpha-1 Ligand 2-(3-c... 5 72
Epidermal growth factor receptor Ligand 3-(3-chloro-phenyl)-5,... 10 64
Prostaglandin G/H synthase 2 Inhibitor 3,4-dibenzyloxy-2'-hydr... 7 40
Liver carboxylesterase 1 Inhibitor 2-methoxy-3,4-methylenediox... 4 26
Amine oxidase [flavin-containing] B and Amine oxidase [flavin-... 2 7
Histone deacetylase 2 and Histone deacetylase 8 inhibitor 2-hy... 1 0
NS5B protein inhibitor (Z)-4-[2-(3-cyanopropoxy)phenyl]-4-hydr... 2 0
Indoleamine 2,3-dioxygenase 1 inhibitor AGN-PC-04S2CP family 1 3
Putative NP ZINC04043753 Family 8 6
benzofuran-2-one NP 5-hydroxybenzofuran-2(3h)-one Family 1 0
2-(2-methoxyphenyl)-5-oxooxolane-3-carboxylate NP ZINC00132596... 4 2


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00422225 CHEMBL2408244 Bioactive 6-(2,5-dimethoxyphenyl)-2-hydroxycyclohepta-2,4,6-trien-1-one
CFAMM00422227 CHEMBL2408240 Bioactive AC1LDAG2

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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