CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM13417
Family Name Histone deacetylase 1 and Proto-oncogene tyrosine-protein kinase Src inhibitor 6-[4-[3-[4-amino-3-(4-chlorophenyl)pyrazolo[3,4-d]pyrimidin-1-yl]phenyl]triazol-1-yl]-N-hydroxyhexanamide family
No. of Seeds 4 No. of Other Members 0
Family Centroid CFAMM00316214 Functional Category Bioactive
Superfamily Potassium voltage-gated channel subfamily A member 5 and Acyl-CoA desaturase 1 Binder Superfamily
Class Class 1567

Cousin Family NamesSeedsMembers
RAC-gamma serine/threonine-protein kinase Inhibitor AZD5363 Fa... 35 69
Melanocortin receptor Ligand Ac-his-dphe(3,4-dicl)-arg-trp-nh2... 10 14
Mitogen-activated protein kinase 14 inhibitor AGN-PC-07ZYJE fa... 15 5
Mitogen-activated protein kinase 13 inhibitor N-cyclopropyl-3-... 16 40
Adenosine receptor A3 ligand AGN-PC-07N4XX family 6 10
Platelet-activating factor receptor ligand SureCN9384429 family 11 3
Dipeptidyl peptidase 8 and Dipeptidyl peptidase 4 inhibitor Su... 5 13
Adenosine receptor A3 ligand N-(5-methyl-2-phenylpyrazolo[4,3-... 5 8
Tyrosine-protein kinase JAK2 inhibitor N-[2-(3-chlorophenyl)-5... 2 11
Prelamin-A/C inhibitor CHEMBL1472945 family 1 32
cGMP-dependent 3',5'-cyclic phosphodiesterase and cAMP and cAM... 8 13
Tyrosine-protein kinase JAK2 inhibitor AGN-PC-09QM1E family 8 15
Prothrombin inhibitor AGN-PC-09QLAK family 10 2
Nociceptin receptor and Potassium voltage-gated channel subfam... 10 1
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subun... 3 11
Adenosine receptor A3 and Adenosine receptor A1 ligand CHEMBL1... 7 4
Hepatocyte growth factor receptor ligand 5-[(6-phenyl-[1,2,4]t... 6 2
Aurora kinase B and Aurora kinase A inhibitor 4-amino-N-[3-[[(... 5 3
Tyrosine-protein kinase JAK2 inhibitor N-[3-(3-chlorophenyl)-1... 12 4
Tyrosine-protein kinase JAK2 and Cytochrome P450 3A4 inhibitor... 1 1
Serine/threonine-protein kinase pim-1 and Serine/threonine-pro... 17 0
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10... 5 6
P2X purinoceptor 7 inhibitor SureCN109149 family 8 1
P2X purinoceptor 7 inhibitor SureCN9931311 family 2 0
Tyrosine-protein kinase SYK inhibitor N-tert-butyl-2-(6-fluoro... 5 1
Tyrosine-protein kinase SYK inhibitor N-tert-butyl-2-(6-chloro... 2 0
Tyrosine-protein kinase JAK3 and Tyrosine-protein kinase JAK2 ... 12 3
RAF proto-oncogene serine/threonine-protein kinase and Serine/... 4 3
Mitogen-activated protein kinase 14 inhibitor 3-[(6-amino-1-ph... 9 2
Serine/threonine-protein kinase B-raf inhibitor 1-[2-[[4-[2-cy... 2 0
Corticotropin-releasing factor receptor 1 and Corticotropin-re... 2 1


CFAM Mol ID

External ID

Functional Category

Molecule Name


Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

26854 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


All rights reserved.

   
 
 
Computer-aided Drug Design
about BIDD |  databases |  software |  teaching |  research |  links

 

Department of Computational Science | National University of Singapore | Blk S17, 3 Science Drive 2, Singapore 117543