CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM13449
Family Name Peroxisome proliferator-activated receptor delta and Peroxisome proliferator-activated receptor gamma ligand 3-[4-[(3R)-3-(4-ethyl-2-thiophen-2-ylphenoxy)butoxy]-2-methylphenyl]propanoic acid family
No. of Seeds 4 No. of Other Members 5
Family Centroid CFAMM00422425 Functional Category Bioactive
Superfamily Peroxisome proliferator-activated receptor gamma and Prostacyclin receptor Binder Superfamily
Class Class 2011

Cousin Family NamesSeedsMembers
Free fatty acid receptor 1 Ligand TAK-875 Family 2 54
Neutrophil elastase Inhibitor CE-1037 Family 1 4
Cannabinoid receptor 2 Ligand 2-(2-methoxybenzyl)-3h-benzo[f]c... 6 32
Hormone-sensitive lipase Inhibitor 2-(3-methoxybenzylthio)-2-p... 1 19
Leukotriene B4 receptor 1 ligand AGN-PC-04XMB7 family 3 18
Prostaglandin E2 receptor EP3 subtype and D(2) dopamine recept... 2 24
Retinoic acid receptor RXR-alpha and Retinoic acid receptor RX... 12 10
Thyroid hormone receptor beta ligand SureCN8891056 family 2 3
Retinoic acid receptor gamma and Retinoic acid receptor alpha ... 1 5
Peroxisome proliferator-activated receptor alpha and Peroxisom... 1 7
Free fatty acid receptor 1 ligand 3-[4-[[3-[4-(1,1-dioxothian-... 3 0
Endothelin-1 receptor and Endothelin B receptor ligand AGN-PC-... 4 12
Cysteinyl leukotriene receptor 1 ligand 4-[(E)-1-carboxy-6-[4-... 2 9
Prostaglandin E2 receptor EP1 subtype and Thromboxane A2 recep... 1 9
Tyrosine-protein phosphatase non-receptor type 1 ligand 2-[4-[... 12 9
Peroxisome proliferator-activated receptor alpha and Arachidon... 1 1
Lethal(3)malignant brain tumor-like protein 1 inhibitor CHEMBL... 1 0
Peroxisome proliferator-activated receptor delta and Peroxisom... 1 0


External ID

Functional Category

Molecule Name

CFAMM00422426 CHEMBL514337 Bioactive SureCN14567156
CFAMM00422425 CHEMBL241078 Bioactive 3-[4-[(3R)-3-(4-ethyl-2-thiophen-2-ylphenoxy)butoxy]-2-methylphenyl]propanoic acid

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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