CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM13452
Family Name Carbonic anhydrase 2 and Carbonic anhydrase 12 inhibitor 5-[1-(4-methylphenyl)triazol-4-yl]thiophene-2-sulfonamide family
No. of Seeds 7 No. of Other Members 5
Family Centroid CFAMM00422451 Functional Category Bioactive
Superfamily Carbonic anhydrase 2 and Carbonic anhydrase 12 Binder Superfamily 8
Class Class 4981

Cousin Family NamesSeedsMembers
5-hydroxytryptamine receptor 6 Ligand 4-(1h-indol-1-ylsulfonyl... 7 79
5-hydroxytryptamine receptor 6 Ligand 6-tosyl-1,2,3,4,5,6-hexa... 4 22
Survival motor neuron protein and 15-hydroxyprostaglandin dehy... 1 35
5-hydroxytryptamine receptor 2A ligand SureCN5215979 family 2 10
Carbonic anhydrase 2 and Carbonic anhydrase 9 inhibitor 5-(1-p... 4 1
Carbonic anhydrase 2 and Carbonic anhydrase 12 inhibitor 5-[1-... 2 0
Carbonic anhydrase 2 and Carbonic anhydrase 5A, mitochondrial ... 3 3


External ID

Functional Category

Molecule Name

CFAMM00422452 CHEMBL2414064 Bioactive 5-[1-(3-methylphenyl)triazol-4-yl]thiophene-2-sulfonamide
CFAMM00422458 CHEMBL2414068 Bioactive 5-(1-naphthalen-1-yltriazol-4-yl)thiophene-2-sulfonamide
CFAMM00422451 CHEMBL2414065 Bioactive 5-[1-(4-methylphenyl)triazol-4-yl]thiophene-2-sulfonamide
CFAMM00422450 CHEMBL2414066 Bioactive 5-[1-(4-tert-butylphenyl)triazol-4-yl]thiophene-2-sulfonamide
CFAMM00422456 CHEMBL2413089 Bioactive 5-[1-[4-(trifluoromethyl)phenyl]triazol-4-yl]thiophene-2-sulfonamide
CFAMM00422449 CHEMBL2414070 Bioactive 5-[1-(3-cyanophenyl)triazol-4-yl]thiophene-2-sulfonamide
CFAMM00422455 CHEMBL2414076 Bioactive 5-[1-[4-cyano-3-(trifluoromethyl)phenyl]triazol-4-yl]thiophene-2-sulfonamide

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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