CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM1346
Family Name 5-hydroxytryptamine receptor 1A and Alpha-1B adrenergic receptor ligand AGN-PC-075M5W family
No. of Seeds 5 No. of Other Members 29
Family Centroid CFAMM00322360 Functional Category Bioactive
Superfamily 5-hydroxytryptamine receptor 1A and Alpha-1B adrenergic receptor Binder Superfamily
Class Class 3346

Cousin Family NamesSeedsMembers
Oxysterols receptor LXR Ligand T0901317 Family 13 68
Delta-type opioid receptor and Kappa-type opioid receptor Liga... 11 3
Oxysterols receptor LXR-alpha and Oxysterols receptor LXR-beta... 4 8
D(2) dopamine receptor and D(3) dopamine receptor Ligand D-237... 21 56
Mu-type opioid receptor ligand N-[(3S,4R)-1-[(2S)-2-hydroxy-2-... 11 4
Acetylcholinesterase inhibitor (2S)-2-(4-aminophenyl)-4,4-dime... 2 1
Vesicular acetylcholine transporter inhibitor N-ethyl-2-fluora... 2 7
Oxysterols receptor LXR-beta and Oxysterols receptor LXR-alpha... 2 19
Sodium-dependent dopamine transporter and Transporter inhibito... 3 4
D(1A) dopamine receptor and D(3) dopamine receptor ligand 4-[(... 2 3
Sodium-dependent dopamine transporter and Sigma non-opioid int... 3 10
Sodium-dependent noradrenaline transporter and Sodium-dependen... 12 16
D(4) dopamine receptor and 5-hydroxytryptamine receptor 2C lig... 1 7
Oxysterols receptor LXR-beta and Oxysterols receptor LXR-alpha... 2 1
D(1A) dopamine receptor and D(3) dopamine receptor ligand Sure... 1 0
2-(4-aminophenyl)-2-[[(1R,2R)-1-hydroxy-1-phenylpropan-2-yl]-m... 2 1
2,6-dimethyl-1,2,3,4-tetrahydroquinolin-4-ol NP (2r,4s)-6-brom... 3 1


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00322340 CHEMBL134304 Bioactive cyclohexyl-[3-[[4-(2-methylphenyl)piperazin-1-yl]methyl]phenyl]methanol
CFAMM00322353 CHEMBL135129 Bioactive AGN-PC-075M6A
CFAMM00322360 CHEMBL340268 Bioactive AGN-PC-075M5W
CFAMM00322351 CHEMBL1161120 Bioactive AGN-PC-080PMC
CFAMM00322355 CHEMBL135107 Bioactive 2-methyl-1-[3-[[4-(2-methylphenyl)piperazin-1-yl]methyl]phenyl]propan-1-ol

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

27676 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


All rights reserved.

   
 
 
Computer-aided Drug Design
about BIDD |  databases |  software |  teaching |  research |  links

 

Department of Computational Science | National University of Singapore | Blk S17, 3 Science Drive 2, Singapore 117543