CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM13461
Family Name Orexin receptor type 2 and Orexin receptor type 1 ligand 2-(1-benzylsulfonyl-2-methylindolizin-3-yl)-N-[(4-fluorophenyl)methyl]-N-methylacetamide family
No. of Seeds 3 No. of Other Members 0
Family Centroid CFAMM00422491 Functional Category Bioactive
Superfamily Macrophage metalloelastase Inhibitor PF-00356231 Superfamily
Class Class 1827

Cousin Family NamesSeedsMembers
5-hydroxytryptamine receptor 6 Ligand SB-742457 Family 9 66
5-hydroxytryptamine receptor 2A and 5-hydroxytryptamine recept... 14 19
Cellular tumor antigen p53 and Microtubule-associated protein ... 1 8
Translocator protein inhibitor N,N-diethyl-11-(2-fluoroethyl)-... 14 9
Neuropeptide Y receptor type 5 ligand 2-indol-1-yl-N-[4-[(prop... 7 6
Cannabinoid receptor 2 and Cannabinoid receptor 1 ligand AC1M4... 1 0


External ID

Functional Category

Molecule Name

CFAMM00422491 CHEMBL2413371 Bioactive 2-(1-benzylsulfonyl-2-methylindolizin-3-yl)-N-[(4-fluorophenyl)methyl]-N-methylacetamide
CFAMM00422490 CHEMBL2413370 Bioactive N-benzyl-2-(1-benzylsulfonyl-2-methylindolizin-3-yl)-N-methylacetamide
CFAMM00422489 CHEMBL2413520 Bioactive N-[(4-fluorophenyl)methyl]-2-[1-[(4-fluorophenyl)methylsulfonyl]-2-methylindolizin-3-yl]-N-methylacetamide

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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