CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM13478
Family Name Sigma non-opioid intracellular receptor 1 ligand 3-[4-(azepan-1-yl)butyl]-1,3-benzothiazol-2-one family
No. of Seeds 8 No. of Other Members 1
Family Centroid CFAMM00422535 Functional Category Bioactive
Superfamily Indoleamine 2,3-dioxygenase 1 Inhibitor 2,3-dihydrobenzo[d]thiazole-2-thiol Superfamily
Class Class 1478

Cousin Family NamesSeedsMembers
D(2) dopamine receptor Ligand phenothiazine analog Prochlorper... 4 25
Alpha adrenergic receptor ligand phenothiazine derivative Thio... 4 10
Muscarinic acetylcholine receptor M5 ligand phenothiazine deri... 8 37
Histamine H1 receptor ligand phenothiazine derivative Mequitaz... 3 2
5-hydroxytryptamine receptor 6 Ligand 4-(4-benzenesulfonamidop... 4 5
Cholinesterase Inhibitor 1,2-di(10h-phenothiazin-10-yl)ethane-... 1 0
Cholinesterase Inhibitor N-cyclohexyl-1'h-phenothiazine-1'-car... 7 2
Cholinesterase Inhibitor N-p-tolyl-1'h-phenothiazine-1'-carbox... 4 1
Cholinesterase Inhibitor Morpholino(1'h-phenothiazin-1'-yl)met... 2 1
Sigma non-opioid intracellular receptor 1 and Histamine H1 rec... 5 9
Sigma non-opioid intracellular receptor 1 and 5-hydroxytryptam... 18 12
5-hydroxytryptamine receptor 1A and 5-hydroxytryptamine recept... 4 2
Sigma non-opioid intracellular receptor 1 ligand 3-[3-(azepan-... 4 4


External ID

Functional Category

Molecule Name

CFAMM00422530 CHEMBL2414347 Bioactive 3-[3-(azepan-1-yl)propyl]-1,3-benzothiazol-2-one
CFAMM00422529 CHEMBL273084 Bioactive 3-[3-(4-cyclohexylpiperazin-1-yl)propyl]-1,3-benzothiazol-2-one
CFAMM00422535 CHEMBL2414348 Bioactive 3-[4-(azepan-1-yl)butyl]-1,3-benzothiazol-2-one
CFAMM00422528 CHEMBL272608 Bioactive 3-[6-(4-cyclohexylpiperazin-1-yl)hexyl]-1,3-benzothiazol-2-one
CFAMM00422527 CHEMBL406081 Bioactive 3-[5-(4-cyclohexylpiperazin-1-yl)pentyl]-1,3-benzothiazol-2-one
CFAMM00422533 CHEMBL2414409 Bioactive 3-[2-(azocan-1-yl)ethyl]-1,3-benzothiazol-2-one;hydrochloride
CFAMM00422532 CHEMBL2414406 Bioactive 3-[5-(azepan-1-yl)pentyl]-1,3-benzothiazol-2-one
CFAMM00422531 CHEMBL2414407 Bioactive 3-[6-(azepan-1-yl)hexyl]-1,3-benzothiazol-2-one

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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