CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM13480
Family Name Integrin beta-1 and Integrin alpha-4 inhibitor (5R)-5-[[(2R)-2-[[2-[4-(1H-benzimidazol-2-ylamino)phenyl]acetyl]amino]-6-[[(E)-3-pyridin-3-ylprop-2-enoyl]amino]hexanoyl]amino]-6-[(1-carbamoylcyclohexyl)amino]-6-oxohexanoic acid family
No. of Seeds 2 No. of Other Members 3
Family Centroid CFAMM00422548 Functional Category Bioactive
Superfamily Integrin beta-1 and Integrin alpha-5 Binder Superfamily
Class Class 639

Cousin Family NamesSeedsMembers
Vasopressin V1a receptor and Vasopressin V2 receptor Ligand be... 4 301
Folate receptor gamma Ligand Folic Acid Family 4 100
Peptide deformylase, mitochondrial inhibitor folic acid analog... 59 98
Prothrombin Inhibitor Dabigatran Family 7 182
BIBT986 family 7 96
Eluxadoline family 4 85
Integrin alpha-V and Integrin beta-3 Inhibitor SB-223245 Family 27 36
Renin Inhibitor Sul-pro-phe-n-mehis-lva-ile-amp Family 47 54
Melanocortin receptor Ligand Ac-his-dnal(2)-arg-trp-nh2 Family 112 67
Bombesin receptor subtype-3 and Gastrin-releasing peptide rece... 42 7
Mu-type opioid receptor and Mu-type opioid receptor ligand Sur... 5 10
Pol polyprotein inhibitor AC1LAQE0 family 13 4
Pol polyprotein inhibitor Hydroxyethylene deriv. 12 family 13 10
Integrin beta-3 and Integrin alpha-V inhibitor 2-[1-[2-[[4-(1H... 6 2
Integrin alpha-4 inhibitor AC1O7HJM family 3 0
Carbonic anhydrase 9 and Carbonic anhydrase 2 inhibitor AGN-PC... 2 4
Dihydrofolate reductase inhibitor AGN-PC-075RRH family 2 3
Glycogen synthase kinase-3 beta inhibitor 2-(4-fluorophenyl)-N... 4 2
Smoothened homolog inhibitor N-[4-methyl-3-(5-phenyl-1H-imidaz... 1 0
Integrin beta-3 and Integrin alpha-V inhibitor 2-[1-[2-[[4-(1H... 2 8
Cyclin-dependent kinase 2 and Potassium voltage-gated channel ... 12 7
Integrin beta-1 and Integrin alpha-5 inhibitor 2-[(2,6-dimethy... 9 1


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00422548 CHEMBL241445 Bioactive (5R)-5-[[(2R)-2-[[2-[4-(1H-benzimidazol-2-ylamino)phenyl]acetyl]amino]-6-[[(E)-3-pyridin-3-ylprop-2-enoyl]amino]hexanoyl]amino]-6-[(1-carbamoylcyclohexyl)amino]-6-oxohexanoic acid
CFAMM00422544 CHEMBL447354 Bioactive Benzimidazole Antagonist, 5

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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