CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM13483
Family Name Tyrosine-protein kinase JAK2 inhibitor 4-[[8-(4-methoxyphenyl)-[1,2,4]triazolo[1,5-a]pyridin-2-yl]amino]benzoic acid family
No. of Seeds 2 No. of Other Members 1
Family Centroid CFAMM00422563 Functional Category Bioactive
Superfamily Adenosine receptor A1 and Adenosine receptor A3 Binder Superfamily 3
Class Class 3548

Cousin Family NamesSeedsMembers
Hepatocyte growth factor receptor Ligand Amg 208 Family 20 236
MK-6096 family 3 69
Integrin alpha-V and Integrin beta-1 Inhibitor SB-265123 Family 30 170
Adenosine receptor A1 and Adenosine receptor A3 Ligand 4-metho... 1 16
cGMP-specific 3',5'-cyclic phosphodiesterase Inhibitor Cartazo... 11 105
Cyclin-dependent kinase 2 and Cyclin-dependent kinase 4 Inhibi... 19 48
cAMP-specific 3',5'-cyclic phosphodiesterase 4A and cAMP-speci... 2 28
Adenosine receptor A3 ligand AGN-PC-07N4XZ family 4 11
Serine/threonine-protein kinase PLK1 and Serine/threonine-prot... 14 42
Adenosine receptor A3 ligand CHEMBL1834696 family 5 18
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subun... 1 0
Prostaglandin D2 receptor ligand 1-[3-[2-methoxy-6-[2-(4-metho... 6 16
Adenosine receptor A3 ligand AGN-PC-08WSLM family 5 22
Integrin beta-1 and Integrin alpha-4 inhibitor SureCN2059024 f... 6 3
Mitogen-activated protein kinase 14 inhibitor AGN-PC-075YLX fa... 3 1
Tyrosine-protein kinase SYK inhibitor 4-[[3-[8-[(5,6-dimethoxy... 2 0
Vascular endothelial growth factor receptor 2 and Serine/threo... 6 13
Adenosine receptor A1 ligand ethyl 1-(2-chloro-2-phenylethyl)-... 5 1
Mast/stem cell growth factor receptor Kit and Epithelial disco... 3 0
Adenosine receptor A2a and Cytochrome P450 3A4 ligand N-[6-(3,... 5 2
5-hydroxytryptamine receptor 2C and 5-hydroxytryptamine recept... 2 1
Tyrosine-protein kinase JAK2 inhibitor 4-[[8-(1-propan-2-ylpyr... 5 6
Angiopoietin-1 receptor and Vascular endothelial growth factor... 5 0
Nuclear receptor ROR-gamma and Prelamin-A/C ligand ST50133141 ... 1 0
Glycogen synthase kinase-3 beta and Glycogen synthase kinase-3... 4 4
Tyrosine-protein kinase Lck inhibitor AGN-PC-07R5ZB family 4 3


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00422564 CHEMBL2414554 Bioactive 4-[[5-(4-methoxyphenyl)-[1,2,4]triazolo[1,5-a]pyridin-2-yl]amino]benzoic acid
CFAMM00422563 CHEMBL2414533 Bioactive 4-[[8-(4-methoxyphenyl)-[1,2,4]triazolo[1,5-a]pyridin-2-yl]amino]benzoic acid

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

27526 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


All rights reserved.

   
 
 
Computer-aided Drug Design
about BIDD |  databases |  software |  teaching |  research |  links

 

Department of Computational Science | National University of Singapore | Blk S17, 3 Science Drive 2, Singapore 117543