CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM13487
Family Name Tyrosine-protein kinase JAK2 inhibitor AGN-PC-0CSEAG family
No. of Seeds 2 No. of Other Members 1
Family Centroid CFAMM00422588 Functional Category Bioactive
Superfamily Tyrosine-protein kinase JAK2 and Aurora kinase A Binder Superfamily
Class Class 712

Cousin Family NamesSeedsMembers
Mast/stem cell growth factor receptor Kit and Vascular endothe... 6 34
Hepatocyte growth factor receptor Ligand SGX523 Family 1 15
Tyrosine-protein kinase Lck and Aurora kinase B Inhibitor VX-6... 28 56
PF-4217903 family 14 65
Corticotropin-releasing factor receptor 1 Ligand R121919 Family 26 84
Interleukin-1 receptor type 1 and Mitogen-activated protein ki... 7 151
Vascular endothelial growth factor receptor 1 and Vascular end... 6 23
Type-2 angiotensin II receptor Ligand L-158282 Family 24 58
5-hydroxytryptamine receptor 6 and 5-hydroxytryptamine recepto... 13 100
5-hydroxytryptamine receptor 6 ligand AGN-PC-0BIUF2 family 25 11
5-hydroxytryptamine receptor 6 and 5-hydroxytryptamine recepto... 2 0
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subun... 3 2
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subun... 4 27
5-hydroxytryptamine receptor 6 ligand 3-(benzenesulfonyl)-N,5-... 4 1
5-hydroxytryptamine receptor 6 ligand 3-(3-chlorophenyl)sulfon... 6 0
Tyrosine-protein kinase JAK2 inhibitor AGN-PC-07CBUP family 2 3
Glucose-dependent insulinotropic receptor ligand 4-({Ethyl-[1-... 6 12
Nociceptin receptor and Potassium voltage-gated channel subfam... 10 1
Receptor-type tyrosine-protein kinase FLT3 and Aurora kinase A... 3 5
Tyrosine-protein kinase JAK2 inhibitor N-tert-butyl-3-[2-[3-fl... 4 14
Aurora kinase A and Cyclin-dependent kinase 1 inhibitor N-[4-[... 12 2
Tyrosine-protein kinase JAK2 and ALK tyrosine kinase receptor ... 5 0
Tyrosine-protein kinase JAK2 inhibitor N-[2-[2-[3-chloro-4-(4-... 2 0
Tyrosine-protein kinase JAK2 and Focal adhesion kinase 1 inhib... 11 3
Tyrosine-protein kinase JAK2 and Tyrosine-protein kinase JAK3 ... 14 1
Casein kinase II subunit alpha inhibitor 7-(cyclopropylamino)-... 1 0
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subun... 2 2
Gamma-aminobutyric acid receptor subunit pi and GABA theta sub... 2 0
5-hydroxytryptamine receptor 6 ligand 8-(1-pyrrolidin-3-ylpyrr... 1 0
5-hydroxytryptamine receptor 2B ligand SureCN1299053 family 1 1
Aurora kinase A and Glycogen synthase kinase-3 beta inhibitor ... 2 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00422589 CHEMBL2414547 Bioactive AGN-PC-0CSEAM
CFAMM00422588 CHEMBL2414545 Bioactive AGN-PC-0CSEAG

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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