CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM13494
Family Name Melanocortin receptor 4 ligand CHEMBL2415084 family
No. of Seeds 3 No. of Other Members 0
Family Centroid CFAMM00422616 Functional Category Bioactive
Superfamily Glucagon receptor and Placenta growth factor Binder Superfamily
Class Class 4560

Cousin Family NamesSeedsMembers
Leutinizing-hormone-releasing hormone inhibitor peptide Leupro... 43 911
Epidermal Growth Factor family 111 209
Parathyroid hormone/parathyroid hormone-related peptide recept... 55 256
Insulin-degrading enzyme inhibitor cyclic polypeptide Bacitrac... 30 259
Renin Inhibitor Enalkiren Family 56 44
Renin Inhibitor Sul-pro-phe-n-mehis-lva-ile-amp Family 47 54
Melanocortin receptor Ligand Ac-his-dnal(2)-arg-trp-nh2 Family 112 67
Type-1 angiotensin II receptor Ligand [sar1,tdf3]angii Family 135 2
Bombesin receptor subtype-3 and Gastrin-releasing peptide rece... 42 7
Placenta growth factor inhibitor CHEMBL1689479 family 4 1
Relaxin-3 receptor 1 and Relaxin-3 receptor 2 ligand CHEMBL203... 4 1
Melanocortin receptor 4 and Melanocortin receptor 5 ligand CHE... 1 0
Melanocortin receptor 4 ligand CHEMBL2331674 family 1 11
Gastrin/cholecystokinin type B receptor ligand CHEMBL2386885 f... 2 1
Mu-type opioid receptor and Delta-type opioid receptor ligand ... 1 0
Melanocyte-stimulating hormone receptor and Melanocortin recep... 1 0
Epidermal growth factor receptor ligand CHEMBL437469 family 1 0
Glucagon receptor ligand CHEMBL267876 family 1 0


External ID

Functional Category

Molecule Name

CFAMM00422617 CHEMBL2415081 Bioactive CHEMBL2415081
CFAMM00422616 CHEMBL2415084 Bioactive CHEMBL2415084
CFAMM00422615 CHEMBL430079 Bioactive CHEMBL430079

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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