CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM13498
Family Name Nicotinamide phosphoribosyltransferase inhibitor N-[[4-(3,5-difluorophenyl)sulfonylphenyl]methyl]-1,3-dihydropyrrolo[3,4-c]pyridine-2-carboxamide family
No. of Seeds 4 No. of Other Members 8
Family Centroid CFAMM00422627 Functional Category Bioactive
Superfamily Nicotinamide phosphoribosyltransferase and Cytochrome P450 2C9 Binder Superfamily 2
Class Class 64

Cousin Family NamesSeedsMembers
Solute carrier family 12 member 1 Inhibitor Torasemide Family 13 75
Corticosteroid 11-beta-dehydrogenase isozyme 1 Inhibitor 2-(4-... 8 25
Potassium voltage-gated channel subfamily H member 2 Ligand AZ... 21 42
Hepatocyte growth factor receptor Ligand 3-(phenylsulfonyl)-1h... 17 59
Carbonic anhydrase 1 and Carbonic anhydrase 2 Inhibitor 4-(2-p... 2 9
Vasopressin V1a receptor and Vasopressin V1b receptor Ligand D... 10 19
Neuropeptide Y receptor type 5 ligand 2-[4-(benzenesulfonamido... 2 27
Thyrotropin receptor and Huntingtin ligand CHEMBL1333081 family 1 2
Corticosteroid 11-beta-dehydrogenase isozyme 1 inhibitor (2R)-... 5 10
Nicotinamide phosphoribosyltransferase and Prelamin-A/C inhibi... 1 0
Collagenase 3 and 72 kDa type IV collagenase inhibitor (2R)-N-... 3 2
Neuronal acetylcholine receptor subunit alpha-7 ligand 1-(4-me... 1 0
cAMP-specific 3',5'-cyclic phosphodiesterase 4A and cAMP-speci... 4 0
Coagulation factor X inhibitor 6-chloro-N-[1-(2-fluoro-4-pyrid... 6 7
Nicotinamide phosphoribosyltransferase inhibitor 1-[4-(8-oxa-3... 5 4
Nicotinamide phosphoribosyltransferase and Cytochrome P450 2C9... 4 5
Nicotinamide phosphoribosyltransferase inhibitor 1-[4-(1-methy... 1 4
Nicotinamide phosphoribosyltransferase and Cytochrome P450 2C9... 1 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00422630 CHEMBL2417572 Bioactive N-[(4-cyclohexylsulfonylphenyl)methyl]-1,3-dihydropyrrolo[3,4-c]pyridine-2-carboxamide
CFAMM00422628 CHEMBL2419536 Bioactive N-[[4-(4-pyrrolidin-1-ylpiperidin-1-yl)sulfonylphenyl]methyl]-1,3-dihydropyrrolo[3,4-c]pyridine-2-carboxamide
CFAMM00422627 CHEMBL2419514 Bioactive N-[[4-(3,5-difluorophenyl)sulfonylphenyl]methyl]-1,3-dihydropyrrolo[3,4-c]pyridine-2-carboxamide
CFAMM00422625 CHEMBL2419512 Bioactive N-[[4-[3-(trifluoromethyl)phenyl]sulfonylphenyl]methyl]-1,3-dihydropyrrolo[3,4-c]pyridine-2-carboxamide

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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