CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM13504
Family Name Coagulation factor VII inhibitor 2-[2-[(1-aminoisoquinolin-6-yl)carbamoyl]-6-(ethylamino)pyridin-3-yl]-5-(2,2-dimethylpropylcarbamoyl)benzoic acid family
No. of Seeds 1 No. of Other Members 14
Family Centroid CFAMM00422672 Functional Category Bioactive
Superfamily Casein kinase II subunit alpha Inhibitor CX-4945 Superfamily
Class Class 1253

Cousin Family NamesSeedsMembers
Peptide deformylase, mitochondrial inhibitor folic acid analog... 59 98
JAK Inhibitor Momelotinib Family 33 83
XL-888 family 16 85
Proto-oncogene tyrosine-protein kinase Src Inhibitor 5,7-diphe... 2 11
Dihydrofolate reductase inhibitor AGN-PC-075RRH family 2 3
B1 bradykinin receptor ligand AGN-PC-005XAO family 3 17
Mast/stem cell growth factor receptor Kit and Mitogen-activate... 4 2
Egl nine homolog 2 and Egl nine homolog 1 inhibitor 3-methyl-4... 15 14
B1 bradykinin receptor ligand methyl 2-fluoro-6-[3-fluoro-4-[[... 22 11
Lysine--tRNA ligase inhibitor 4-[[2-(2-piperazin-1-ylpyridin-4... 2 0
B1 bradykinin receptor ligand methyl 2-[4-[(1R)-1-[[3-[(2-cyan... 8 7
Integrin alpha-V and Integrin beta-6 inhibitor 3-[[2-[4-[(4-me... 4 3
Coagulation factor VII and Coagulation factor X inhibitor Ono ... 2 4
Coagulation factor X and Tissue factor inhibitor AGN-PC-02WN8Y... 7 22
Beta-3 adrenergic receptor ligand SureCN5704018 family 4 1
Serine/threonine-protein kinase Sgk1 inhibitor SureCN3774571 f... 2 18
Integrin beta-1 and Integrin alpha-5 inhibitor 2-[(2,6-dimethy... 9 1


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00422672 CHEMBL2417903 Bioactive 2-[2-[(1-aminoisoquinolin-6-yl)carbamoyl]-6-(ethylamino)pyridin-3-yl]-5-(2,2-dimethylpropylcarbamoyl)benzoic acid

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

26827 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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