CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM13545
Family Name Methionine aminopeptidase 2 inhibitor SureCN5373581 family
No. of Seeds 6 No. of Other Members 0
Family Centroid CFAMM00422877 Functional Category Bioactive
Superfamily Methionine aminopeptidase 2 and Ferritin light chain Binder Superfamily
Class Class 1600

Cousin Family NamesSeedsMembers
Alpha-2 adrenergic receptor Ligand Dexmedetomidine Family 32 639
Type-1 angiotensin II receptor Ligand Forasartan Family 3 253
Metabotropic glutamate receptor 5 Ligand ADX-48621 Family 15 444
C-X-C chemokine receptor type 4 Ligand AMD-070 Family 12 800
Vascular endothelial growth factor Inhibitor PTC299 Family 6 145
Fibroblast growth factor receptor 2 and Fibroblast growth fact... 11 86
Histamine H3 receptor and Histamine H4 receptor Ligand Clobenp... 31 38
Interleukin-1 receptor type 1 and Mitogen-activated protein ki... 7 151
Alpha-1A adrenergic receptor and Alpha-1B adrenergic receptor ... 4 22
Arachidonate 5-lipoxygenase Inhibitor 2,4,5-triarylimidazole A... 3 16
Methionine aminopeptidase 2 Inhibitor 2-(pyridin-2-yl)-1h-benz... 6 19
Mitogen-activated protein kinase 14 and Tyrosine-protein kinas... 1 9
Alpha-1A adrenergic receptor Ligand A-315456 Family 7 17
Indoleamine 2,3-dioxygenase 1 Inhibitor 3-(4h-imidazol-4-yl)be... 6 3
RAF proto-oncogene serine/threonine-protein kinase Inhibitor L... 219 124
Histamine H3 receptor Ligand 4-(2-(phenylamino)ethyl)-1h-imida... 5 16
Gamma-aminobutyric acid receptor subunit alpha-1 and Gamma-ami... 6 55
Xanthine dehydrogenase/oxidase Inhibitor 3,5-di(pyridin-4-yl)-... 6 3
Cytochrome P450 2D6 and Cytochrome P450 3A4 Inhibitor 2-(2-(4-... 25 10
Adenosine receptor A3 and Adenosine receptor A2a ligand 5-buty... 3 13
Histamine H3 receptor ligand SureCN7853275 family 2 5
Adenosine receptor A1 and Adenosine receptor A2b ligand SureCN... 1 0
Tyrosine-protein kinase JAK2 and Tyrosine-protein kinase JAK3 ... 9 3
Receptor-type tyrosine-protein kinase FLT3 and Mast/stem cell ... 2 1
Serine/threonine-protein kinase mTOR and Phosphatidylinositol ... 2 1
Motilin receptor ligand SureCN2004322 family 2 1
Methionine aminopeptidase 2 inhibitor SureCN5376630 family 1 0
Nociceptin receptor ligand 6-fluoro-2-pentan-3-ylsulfanyl-5-pi... 1 4
5-hydroxytryptamine receptor 3A ligand AGN-PC-077D8K family 3 1
Tyrosyl-DNA phosphodiesterase 1 and Putative fructose-1,6-bisp... 1 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00422872 CHEMBL242272 Bioactive SureCN5381705
CFAMM00422877 CHEMBL243322 Bioactive SureCN5373581
CFAMM00422876 CHEMBL437011 Bioactive SureCN5384772
CFAMM00422875 CHEMBL398228 Bioactive AGN-PC-015HYN
CFAMM00422874 CHEMBL242052 Bioactive SureCN5374262
CFAMM00422873 CHEMBL395715 Bioactive SureCN5374391

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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