CFam Chemical Families Database
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Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM13549
Family Name Nicotinamide phosphoribosyltransferase inhibitor N-[[4-(benzenesulfonyl)phenyl]methyl]thieno[2,3-c]pyridine-2-carboxamide family
No. of Seeds 4 No. of Other Members 4
Family Centroid CFAMM00422904 Functional Category Bioactive
Superfamily Macrophage metalloelastase Inhibitor PF-00356231 Superfamily
Class Class 1827

Cousin Family NamesSeedsMembers
Macrophage metalloelastase Inhibitor PF-00356231 Family 5 79
Carbonic anhydrase 2 Inhibitor N-[2-(1h-indol-5-yl)-butyl]-4-s... 12 70
Integrin beta-3 Inhibitor L-739758 Family 2 4
Histone deacetylase 1 Inhibitor N-hydroxy-5-(pyridin-3-yl)thio... 9 46
Mitogen-activated protein kinase 14 Inhibitor N-(4-fluorobenzy... 19 32
Phosphoribosylaminoimidazolecarboxamide formyltransferase Inhi... 1 13
5-hydroxytryptamine receptor 1A and D(3) dopamine receptor lig... 2 8
Tyrosine-protein kinase JAK2 and Tyrosine-protein kinase JAK1 ... 8 1
Prostaglandin E2 receptor EP4 subtype ligand AGN-PC-09QJ7P family 2 0
Neuromedin-K receptor ligand 3-methylsulfinyl-N-[(1S)-1-phenyl... 3 5
Gamma-aminobutyric acid receptor subunit gamma-2 and Gamma-ami... 4 11
Glycogen synthase kinase-3 beta and Cyclin-dependent kinase 2 ... 1 2
Glycogen synthase kinase-3 beta inhibitor 7-(6-chloropyridin-2... 2 3
Neuronal acetylcholine receptor subunit alpha-7 ligand AGN-PC-... 7 1
Neuronal acetylcholine receptor subunit alpha-7 and Neuronal a... 8 5
Metabotropic glutamate receptor 1 and Metabotropic glutamate r... 8 4
Cyclin-dependent kinase 8 and Cyclin-dependent kinase 5 inhibi... 1 6
cAMP-specific 3',5'-cyclic phosphodiesterase 4B and cAMP-speci... 5 5
Cell division cycle 7-related protein kinase and Protein DBF4 ... 2 1
Histone deacetylase 1 inhibitor N-hydroxy-5-[1-[2-[(1-methylin... 4 1
Histone deacetylase 1 inhibitor 5-[5-[[(2-chlorophenyl)methyla... 4 1
Mitogen-activated protein kinase 14 and Mitogen-activated prot... 4 0
Nicotinamide phosphoribosyltransferase inhibitor N-[[4-(3-fluo... 6 4
cAMP-specific 3',5'-cyclic phosphodiesterase 4B inhibitor 6-(b... 5 5
Intercellular adhesion molecule 1 and E-selectin inhibitor Sur... 1 0
Serine/threonine-protein kinase Chk1 and Cyclin-dependent kina... 2 1
5-hydroxytryptamine receptor 6 ligand AGN-PC-07CR33 family 2 2
Carbonic anhydrase 2 and Carbonic anhydrase 4 inhibitor AGN-PC... 2 2
Vasopressin V2 receptor and Vasopressin V1a receptor ligand N-... 1 1
Calpain-1 catalytic subunit inhibitor 2,5-dichloro-N-[(2S)-3,4... 2 0
Intercellular adhesion molecule 1 and E-selectin inhibitor Sur... 1 2


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00422909 CHEMBL2420627 Bioactive N-[[4-[3-(trifluoromethyl)phenyl]sulfonylphenyl]methyl]thieno[2,3-c]pyridine-2-carboxamide
CFAMM00422908 CHEMBL2420626 Bioactive N-[[4-(3,5-difluorophenyl)sulfonylphenyl]methyl]thieno[2,3-c]pyridine-2-carboxamide
CFAMM00422907 CHEMBL2420661 Bioactive N-[(4-piperidin-1-ylsulfonylphenyl)methyl]thieno[2,3-b]pyridine-2-carboxamide
CFAMM00422904 CHEMBL2420659 Bioactive N-[[4-(benzenesulfonyl)phenyl]methyl]thieno[2,3-c]pyridine-2-carboxamide

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

27075 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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