CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM13552
Family Name Nicotinamide phosphoribosyltransferase inhibitor N-[[4-(benzenesulfonyl)phenyl]methyl]imidazo[1,2-a]pyrimidine-6-carboxamide family
No. of Seeds 4 No. of Other Members 0
Family Centroid CFAMM00422919 Functional Category Bioactive
Superfamily Glycogen synthase kinase-3 beta and Nicotinamide phosphoribosyltransferase Binder Superfamily
Class Class 853

Cousin Family NamesSeedsMembers
Potassium voltage-gated channel subfamily H member 2 Ligand AZ... 21 42
Hepatocyte growth factor receptor Ligand 3-(phenylsulfonyl)-1h... 17 59
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subun... 4 27
Carbonic anhydrase 9 and Carbonic anhydrase 2 inhibitor AGN-PC... 2 4
5-hydroxytryptamine receptor 2C and 5-hydroxytryptamine recept... 9 1
Tyrosine-protein kinase JAK2 inhibitor AGN-PC-07CBUP family 2 3
5-hydroxytryptamine receptor 2A and 5-hydroxytryptamine recept... 5 3
Nicotinamide phosphoribosyltransferase and Cytochrome P450 2C9... 4 5
Tyrosine-protein kinase JAK2 inhibitor N,N-dimethyl-4-[[8-(4-m... 2 1
Nicotinamide phosphoribosyltransferase inhibitor N-[[4-(3,5-di... 2 0
Nicotinamide phosphoribosyltransferase inhibitor N-[[4-(6-morp... 2 0


External ID

Functional Category

Molecule Name

CFAMM00422919 CHEMBL2420638 Bioactive N-[[4-(benzenesulfonyl)phenyl]methyl]imidazo[1,2-a]pyrimidine-6-carboxamide
CFAMM00422918 CHEMBL2420632 Bioactive N-[[4-(3,5-difluorophenyl)sulfonylphenyl]methyl]imidazo[1,2-a]pyrimidine-6-carboxamide
CFAMM00422917 CHEMBL2420633 Bioactive N-[[4-[3-(trifluoromethyl)phenyl]sulfonylphenyl]methyl]imidazo[1,2-a]pyrimidine-6-carboxamide
CFAMM00422916 CHEMBL2420637 Bioactive N-[(4-piperidin-1-ylsulfonylphenyl)methyl]imidazo[1,2-a]pyrimidine-6-carboxamide

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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