CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM13577
Family Name Dipeptidyl peptidase 4 and Dipeptidyl peptidase 8 inhibitor (2R,3S,5R)-2-(2,5-difluorophenyl)-5-[2-(trifluoromethyl)-4,6-dihydro-1H-pyrrolo[3,4-d]imidazol-5-yl]oxan-3-amine family
No. of Seeds 2 No. of Other Members 1
Family Centroid CFAMM00307205 Functional Category Bioactive
Superfamily Substance-P receptor and DNA gyrase subunit B Binder Superfamily
Class Class 1855

Cousin Family NamesSeedsMembers
Histamine H1 receptor Ligand Emedastine Family 5 115
Grt 6005/06 family 4 22
DNA Binder Bisbenzimide (hoechst 33258) Family 4 159
Substance-P receptor ligand (2S,3S)-3-[[3,5-bis(trifluoromethy... 2 1
Neuropeptide Y receptor type 5 ligand 2-phenyl-4-(6-propylsulf... 12 5
Integrin beta-3 and Integrin alpha-V inhibitor (2S)-3-[4-[4-[(... 9 7


External ID

Functional Category

Molecule Name

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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