CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM1358
Family Name Pol polyprotein inhibitor (2R,3R,4R,5R)-2,3,4-trihydroxy-N,N'-bis[(2S)-2-hydroxy-2,3-dihydro-1H-inden-1-yl]-5-phenoxyhexanediamide family
No. of Seeds 3 No. of Other Members 3
Family Centroid CFAMM00322520 Functional Category Bioactive
Superfamily Pol polyprotein and Plasmepsin-1 Binder Superfamily
Class Class 3085

Cousin Family NamesSeedsMembers
Pol polyprotein inhibitor AC1LAK4B family 16 11
Pol polyprotein inhibitor (2R,3R,4R,5R)-3,4-dihydroxy-N-[(2S)-... 22 10
72 kDa type IV collagenase and Matrix metalloproteinase-9 inhi... 3 4
Pol polyprotein inhibitor MK-944a family 6 1
Renin inhibitor N-[(2S,4S,5S,7S)-7-[2-(1-acetylpiperidin-4-yl)... 2 1
Pol polyprotein inhibitor (2R)-2-benzyl-5-[(3S,5R)-3-benzyl-5-... 11 5
Pol polyprotein inhibitor AC1LADII family 12 1
Pol polyprotein inhibitor L-689,502 family 17 2
Pol polyprotein inhibitor SDZ PRI 053 family 8 1
Plasmepsin-1 and Plasmepsin-2 inhibitor C2-symmetric compound ... 2 0
Plasmepsin-2 and Plasmepsin-1 inhibitor (2R,3R,4R,5R)-2,5-bis[... 2 2


External ID

Functional Category

Molecule Name

CFAMM00322520 CHEMBL1161742 Bioactive (2R,3R,4R,5R)-2,3,4-trihydroxy-N,N'-bis[(2S)-2-hydroxy-2,3-dihydro-1H-inden-1-yl]-5-phenoxyhexanediamide
CFAMM00322516 CHEMBL1161736 Bioactive (2R,3R,4R,5R)-N-[(2S)-2,3-dimethylbutanoyl]-2,3,4-trihydroxy-N'-[(2S)-2-hydroxy-2,3-dihydro-1H-inden-1-yl]-5-phenoxyhexanediamide
CFAMM00322521 CHEMBL425182 Bioactive (2R,3R,5R)-3,5-dihydroxy-N-[(2S)-2-hydroxy-2,3-dihydro-1H-inden-1-yl]-N'-[(2R)-2-hydroxy-2,3-dihydro-1H-inden-1-yl]-2-phenoxyhexanediamide

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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